NTRK3-AS1

Summary

NTRK3-AS1 (NTRK3 antisense RNA 1, HGNC:27532) is a long non-coding RNA gene on chromosome 15q25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27532
Approved symbol	NTRK3-AS1
Name	NTRK3 antisense RNA 1
Location	15q25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260305
Ensembl biotype	lncRNA
Entrez	283738
RNAcentral	URS000042D915 — lncRNA, 2663 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000569588, ENST00000782461, ENST00000782462

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000569588 — 4 exons

Exon	Start	End
ENSE00002580851	88267867	88268086
ENSE00002594790	88252730	88253478
ENSE00002619922	88269465	88271066
ENSE00002620065	88266781	88266872

Expression profiles

Bgee: expression breadth broad, 63 present calls, max score 91.37.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0641 / max 67.6627, expressed in 3 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
148272	0.0362	3
148271	0.0279	3

Top tissues by expression

190 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.37	gold quality
sperm	CL:0000019	80.72	gold quality
parotid gland	UBERON:0001831	75.65	gold quality
saliva-secreting gland	UBERON:0001044	71.93	gold quality
buccal mucosa cell	CL:0002336	71.27	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	70.39	gold quality
cerebellar vermis	UBERON:0004720	70.35	gold quality
right testis	UBERON:0004534	70.08	gold quality
islet of Langerhans	UBERON:0000006	69.78	gold quality
kidney epithelium	UBERON:0004819	68.67	gold quality
left testis	UBERON:0004533	68.51	gold quality
testis	UBERON:0000473	67.23	gold quality
upper arm skin	UBERON:0004263	67.21	gold quality
nasal cavity epithelium	UBERON:0005384	66.73	gold quality
adult organism	UBERON:0007023	66.28	gold quality
skeletal muscle tissue	UBERON:0001134	65.92	gold quality
quadriceps femoris	UBERON:0001377	65.21	gold quality
myocardium	UBERON:0002349	65.03	gold quality
vena cava	UBERON:0004087	64.81	gold quality
left ventricle myocardium	UBERON:0006566	64.81	gold quality
cardiac muscle of right atrium	UBERON:0003379	64.54	gold quality
vastus lateralis	UBERON:0001379	64.41	gold quality
biceps brachii	UBERON:0001507	63.31	gold quality
pharyngeal mucosa	UBERON:0000355	62.97	gold quality
metanephros	UBERON:0000081	62.18	gold quality
decidua	UBERON:0002450	61.69	gold quality
body of tongue	UBERON:0011876	60.84	gold quality
nipple	UBERON:0002030	60.53	gold quality
deltoid	UBERON:0001476	60.39	gold quality
corpus callosum	UBERON:0002336	60.23	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.