NUCB1-AS1

Summary

NUCB1-AS1 (NUCB1 antisense RNA 1, HGNC:40419) is a long non-coding RNA gene on chromosome 19q13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40419
Approved symbol	NUCB1-AS1
Name	NUCB1 antisense RNA 1
Location	19q13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235191
Ensembl biotype	lncRNA
Entrez	100874085
RNAcentral	URS00003B20F9 — lncRNA, 433 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000416432, ENST00000788117

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416432 — 2 exons

Exon	Start	End
ENSE00001620811	48910930	48911174
ENSE00004166364	48918704	48918926

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 96.08.

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
quadriceps femoris	UBERON:0001377	96.08	gold quality
cerebellar vermis	UBERON:0004720	94.69	gold quality
thymus	UBERON:0002370	82.68	silver quality
bone marrow cell	CL:0002092	73.54	gold quality
skeletal muscle tissue	UBERON:0001134	68.31	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	66.62	gold quality
bone marrow	UBERON:0002371	65.90	gold quality
corpus callosum	UBERON:0002336	65.27	gold quality
lymph node	UBERON:0000029	64.68	gold quality
mucosa of transverse colon	UBERON:0004991	64.28	gold quality
liver	UBERON:0002107	63.86	gold quality
right lobe of liver	UBERON:0001114	62.25	gold quality
colonic epithelium	UBERON:0000397	61.79	silver quality
blood	UBERON:0000178	61.76	gold quality
duodenum	UBERON:0002114	61.31	gold quality
tonsil	UBERON:0002372	60.63	gold quality
lower esophagus mucosa	UBERON:0035834	59.28	gold quality
monocyte	CL:0000576	58.83	gold quality
adult mammalian kidney	UBERON:0000082	58.54	gold quality
stromal cell of endometrium	CL:0002255	57.82	gold quality
endometrium	UBERON:0001295	56.83	gold quality
kidney	UBERON:0002113	56.80	gold quality
prefrontal cortex	UBERON:0000451	56.78	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.02	gold quality
primary visual cortex	UBERON:0002436	55.90	gold quality
fundus of stomach	UBERON:0001160	55.69	gold quality
islet of Langerhans	UBERON:0000006	55.46	gold quality
placenta	UBERON:0001987	54.52	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.46	gold quality
spleen	UBERON:0002106	54.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.