NUP133-DT

Summary

NUP133-DT (NUP133 divergent transcript, HGNC:55870) is a long non-coding RNA gene on chromosome 1q42.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55870
Approved symbol	NUP133-DT
Name	NUP133 divergent transcript
Location	1q42.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000223635
Ensembl biotype	lncRNA
Entrez	101927478
RNAcentral	URS000075D2F0 — lncRNA, 477 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000417605, ENST00000849110, ENST00000849111, ENST00000849112, ENST00000849113, ENST00000849114, ENST00000849115, ENST00000849116

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000417605 — 3 exons

Exon	Start	End
ENSE00001654306	229508369	229508679
ENSE00001732267	229510124	229510240
ENSE00004279270	229513978	229514385

Expression profiles

Bgee: expression breadth broad, 86 present calls, max score 88.11.

Top tissues by expression

188 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	88.11	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.78	gold quality
left testis	UBERON:0004533	79.92	gold quality
right testis	UBERON:0004534	79.39	gold quality
testis	UBERON:0000473	78.05	gold quality
upper arm skin	UBERON:0004263	76.00	gold quality
cardiac muscle of right atrium	UBERON:0003379	73.08	gold quality
left ventricle myocardium	UBERON:0006566	72.88	gold quality
kidney epithelium	UBERON:0004819	71.29	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.72	gold quality
epithelial cell of pancreas	CL:0000083	65.97	gold quality
epithelium of nasopharynx	UBERON:0001951	65.88	gold quality
metanephros	UBERON:0000081	64.20	gold quality
secondary oocyte	CL:0000655	64.02	gold quality
adult organism	UBERON:0007023	63.98	gold quality
tibialis anterior	UBERON:0001385	63.63	silver quality
lower lobe of lung	UBERON:0008949	61.20	silver quality
caecum	UBERON:0001153	60.76	gold quality
pons	UBERON:0000988	60.27	gold quality
myocardium	UBERON:0002349	60.22	gold quality
layer of synovial tissue	UBERON:0007616	59.59	gold quality
quadriceps femoris	UBERON:0001377	58.97	gold quality
inferior vagus X ganglion	UBERON:0005363	58.13	gold quality
vastus lateralis	UBERON:0001379	57.99	gold quality
mucosa of paranasal sinus	UBERON:0005030	57.97	gold quality
deltoid	UBERON:0001476	57.92	gold quality
oocyte	CL:0000023	57.79	gold quality
saphenous vein	UBERON:0007318	57.73	gold quality
pericardium	UBERON:0002407	57.62	gold quality
ventral tegmental area	UBERON:0002691	57.51	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.73

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.