NUP153-AS1

Summary

NUP153-AS1 (NUP153 antisense RNA 1, HGNC:55217) is a long non-coding RNA gene on chromosome 6p22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55217
Approved symbol	NUP153-AS1
Name	NUP153 antisense RNA 1
Location	6p22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272269
Ensembl biotype	lncRNA
Entrez	105374952
RNAcentral	URS0000A777EE — lncRNA, 1237 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000606771, ENST00000769169, ENST00000769170, ENST00000769171, ENST00000769172, ENST00000769173, ENST00000769174, ENST00000769175, ENST00000769176, ENST00000769177, ENST00000769178

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000606771 — 2 exons

Exon	Start	End
ENSE00004130063	17710789	17711153
ENSE00004130075	17706094	17707626

Expression profiles

Bgee: expression breadth ubiquitous, 155 present calls, max score 70.36.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.6393 / max 124.1387, expressed in 1439 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
66160	3.9113	1349
66159	0.4586	205
66158	0.2224	75
66161	0.0470	7

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	70.36	gold quality
sural nerve	UBERON:0015488	68.53	gold quality
cartilage tissue	UBERON:0002418	68.09	gold quality
stromal cell of endometrium	CL:0002255	66.79	gold quality
gastrocnemius	UBERON:0001388	65.73	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	65.18	gold quality
muscle of leg	UBERON:0001383	64.98	gold quality
spleen	UBERON:0002106	63.53	gold quality
omental fat pad	UBERON:0010414	63.23	gold quality
peritoneum	UBERON:0002358	63.17	gold quality
right lobe of liver	UBERON:0001114	63.08	gold quality
adipose tissue of abdominal region	UBERON:0007808	62.00	gold quality
vermiform appendix	UBERON:0001154	61.66	gold quality
ventricular zone	UBERON:0003053	61.58	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.89	gold quality
lymph node	UBERON:0000029	60.37	gold quality
colonic epithelium	UBERON:0000397	59.74	silver quality
apex of heart	UBERON:0002098	59.03	gold quality
left adrenal gland cortex	UBERON:0035825	58.97	gold quality
left adrenal gland	UBERON:0001234	58.76	gold quality
leukocyte	CL:0000738	58.58	gold quality
right coronary artery	UBERON:0001625	58.49	gold quality
ganglionic eminence	UBERON:0004023	58.23	gold quality
lower esophagus mucosa	UBERON:0035834	58.19	gold quality
mucosa of transverse colon	UBERON:0004991	58.06	gold quality
monocyte	CL:0000576	57.79	gold quality
esophagus mucosa	UBERON:0002469	57.61	gold quality
subcutaneous adipose tissue	UBERON:0002190	57.39	gold quality
left coronary artery	UBERON:0001626	57.22	gold quality
adrenal gland	UBERON:0002369	57.12	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.