NUP54-DT

Summary

NUP54-DT (NUP54 divergent transcript, HGNC:58820) is a long non-coding RNA gene on chromosome 4q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58820
Approved symbol	NUP54-DT
Name	NUP54 divergent transcript
Location	4q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000286074
Ensembl biotype	lncRNA
Entrez	124900718

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000651366, ENST00000793030, ENST00000793031

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000651366 — 3 exons

Exon	Start	End
ENSE00003849505	76148561	76148602
ENSE00003850914	76199966	76200666
ENSE00003851065	76149207	76149266

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 66.88.

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	66.88	silver quality
colonic epithelium	UBERON:0000397	60.75	silver quality
bone marrow	UBERON:0002371	60.69	gold quality
skeletal muscle tissue	UBERON:0001134	59.99	silver quality
liver	UBERON:0002107	57.77	gold quality
monocyte	CL:0000576	56.89	gold quality
tonsil	UBERON:0002372	54.39	gold quality
corpus callosum	UBERON:0002336	54.32	gold quality
duodenum	UBERON:0002114	53.66	gold quality
endometrium	UBERON:0001295	53.62	gold quality
blood	UBERON:0000178	53.49	silver quality
adrenal tissue	UBERON:0018303	53.44	gold quality
islet of Langerhans	UBERON:0000006	53.25	gold quality
calcaneal tendon	UBERON:0003701	53.14	silver quality
lymph node	UBERON:0000029	51.19	gold quality
pancreas	UBERON:0001264	50.23	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.49	gold quality
right lobe of liver	UBERON:0001114	49.12	silver quality
gall bladder	UBERON:0002110	48.68	gold quality
muscle of leg	UBERON:0001383	48.41	silver quality
kidney	UBERON:0002113	47.93	gold quality
prefrontal cortex	UBERON:0000451	47.87	silver quality
placenta	UBERON:0001987	47.48	gold quality
lung	UBERON:0002048	47.30	gold quality
smooth muscle tissue	UBERON:0001135	47.27	gold quality
gastrocnemius	UBERON:0001388	47.19	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	46.39	silver quality
body of pancreas	UBERON:0001150	46.21	silver quality
ovary	UBERON:0000992	45.78	gold quality
fundus of stomach	UBERON:0001160	45.67	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.