NXN-AS1

Summary

NXN-AS1 (NXN antisense RNA 1, HGNC:58546) is a long non-coding RNA gene on chromosome 17p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58546
Approved symbol	NXN-AS1
Name	NXN antisense RNA 1
Location	17p13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000262133
Ensembl biotype	lncRNA
Entrez	142592813

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000573877

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000573877 — 2 exons

Exon	Start	End
ENSE00002635465	879880	880093
ENSE00004218654	877738	878272

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 69.39.

Top tissues by expression

223 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	69.39	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	64.49	gold quality
bone marrow cell	CL:0002092	63.34	silver quality
hindlimb stylopod muscle	UBERON:0004252	63.17	gold quality
skin of leg	UBERON:0001511	61.99	gold quality
skin of abdomen	UBERON:0001416	61.07	gold quality
zone of skin	UBERON:0000014	60.19	gold quality
spleen	UBERON:0002106	59.61	gold quality
mucosa of stomach	UBERON:0001199	58.92	gold quality
tibial artery	UBERON:0007610	57.57	gold quality
popliteal artery	UBERON:0002250	57.53	gold quality
upper lobe of left lung	UBERON:0008952	56.15	gold quality
calcaneal tendon	UBERON:0003701	55.60	gold quality
muscle of leg	UBERON:0001383	55.48	gold quality
subcutaneous adipose tissue	UBERON:0002190	55.44	gold quality
gastrocnemius	UBERON:0001388	55.14	gold quality
monocyte	CL:0000576	54.88	gold quality
upper lobe of lung	UBERON:0008948	54.60	gold quality
aorta	UBERON:0000947	54.57	gold quality
vermiform appendix	UBERON:0001154	54.53	gold quality
hypothalamus	UBERON:0001898	54.51	gold quality
islet of Langerhans	UBERON:0000006	53.92	gold quality
upper leg skin	UBERON:0004262	53.83	silver quality
buccal mucosa cell	CL:0002336	53.32	gold quality
putamen	UBERON:0001874	52.70	gold quality
uterine cervix	UBERON:0000002	52.68	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	51.99	gold quality
tonsil	UBERON:0002372	51.71	silver quality
saliva-secreting gland	UBERON:0001044	51.66	gold quality
esophagus mucosa	UBERON:0002469	51.62	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.