OLMALINC

Summary

OLMALINC (oligodendrocyte maturation-associated long intergenic non-coding RNA, HGNC:28060) is a long non-coding RNA gene on chromosome 10q24.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:28060
Approved symbol	OLMALINC
Name	oligodendrocyte maturation-associated long intergenic non-coding RNA
Location	10q24.31
Locus type	RNA, long non-coding
Status	Approved
Aliases	bA34D15.5, FLJ12974, HI-LNC80
Ensembl gene	ENSG00000235823
Ensembl biotype	lncRNA
OMIM	616240
Entrez	90271
RNAcentral	URS000075C0D0 — lncRNA, 1003 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 43 — 43 lncRNA

ENST00000454935, ENST00000608396, ENST00000641087, ENST00000641571, ENST00000641708, ENST00000641799, ENST00000654233, ENST00000654288, ENST00000654563, ENST00000656449, ENST00000657262, ENST00000657502, ENST00000658059, ENST00000659075, ENST00000659159, ENST00000659770, ENST00000661096, ENST00000661158, ENST00000662018, ENST00000662712, ENST00000663103, ENST00000664100, ENST00000664224, ENST00000664225, ENST00000664516, ENST00000665022, ENST00000665755, ENST00000666045, ENST00000666154, ENST00000666713, ENST00000667278, ENST00000668101, ENST00000668189, ENST00000668904, ENST00000669693, ENST00000690014, ENST00000768997, ENST00000768998, ENST00000768999, ENST00000769000, ENST00000769001, ENST00000769002, ENST00000769003

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000454935 — 2 exons

Exon	Start	End
ENSE00001636451	100373615	100374012
ENSE00001789955	100381216	100383368

Expression profiles

Bgee: expression breadth ubiquitous, 195 present calls, max score 96.03.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 10.4074 / max 759.8381, expressed in 1561 samples.

FANTOM5 promoters (8 alternative TSS)

Promoter ID	TPM avg	Samples expressed
106578	3.4555	1048
106583	2.9143	898
106579	2.0338	808
106577	0.9988	443
106581	0.4296	232
106576	0.2729	126
106580	0.1723	90
106582	0.1302	49

Top tissues by expression

249 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
C1 segment of cervical spinal cord	UBERON:0006469	96.03	gold quality
islet of Langerhans	UBERON:0000006	94.17	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.11	gold quality
spinal cord	UBERON:0002240	92.26	gold quality
colonic epithelium	UBERON:0000397	91.17	gold quality
hypothalamus	UBERON:0001898	90.34	gold quality
amygdala	UBERON:0001876	89.95	gold quality
ventricular zone	UBERON:0003053	88.39	gold quality
ganglionic eminence	UBERON:0004023	87.93	gold quality
lower esophagus mucosa	UBERON:0035834	87.84	gold quality
anterior cingulate cortex	UBERON:0009835	87.50	gold quality
mucosa of transverse colon	UBERON:0004991	87.29	gold quality
sural nerve	UBERON:0015488	87.04	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	86.80	gold quality
putamen	UBERON:0001874	86.55	gold quality
Brodmann (1909) area 9	UBERON:0013540	86.33	gold quality
right lobe of liver	UBERON:0001114	86.04	gold quality
nucleus accumbens	UBERON:0001882	85.82	gold quality
right frontal lobe	UBERON:0002810	85.74	gold quality
bone marrow cell	CL:0002092	85.61	gold quality
right adrenal gland	UBERON:0001233	85.33	gold quality
right adrenal gland cortex	UBERON:0035827	84.69	gold quality
caudate nucleus	UBERON:0001873	84.67	gold quality
prefrontal cortex	UBERON:0000451	84.30	gold quality
adenohypophysis	UBERON:0002196	84.04	gold quality
minor salivary gland	UBERON:0001830	83.86	gold quality
left ovary	UBERON:0002119	83.72	gold quality
pituitary gland	UBERON:0000007	83.69	gold quality
substantia nigra	UBERON:0002038	83.60	gold quality
right uterine tube	UBERON:0001302	83.42	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	7.47

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• the expression patterns of oligodendrocyte maturation-associated long intervening non-coding RNA (OLMALINC), is reported. (PMID:25575711)
• OLMALINC/OCT4/BMP2 axis enhances osteogenic-like phenotype of renal interstitial fibroblasts to participate in Randall’s plaque formation. (PMID:36581839)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.