OPCML-IT1

Summary

OPCML-IT1 (OPCML intronic transcript 1, HGNC:41366) is a long non-coding RNA gene on chromosome 11q25.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41366
Approved symbol	OPCML-IT1
Name	OPCML intronic transcript 1
Location	11q25
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254896
Ensembl biotype	lncRNA
Entrez	100874333
RNAcentral	URS00025E341E — lncRNA, 2908 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000533859

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000533859 — 2 exons

Exon	Start	End
ENSE00002151646	133365309	133366080
ENSE00002185428	133360029	133362192

Expression profiles

Bgee: expression breadth broad, 25 present calls, max score 53.58.

Top tissues by expression

25 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	53.58	silver quality
blood	UBERON:0000178	50.81	silver quality
prefrontal cortex	UBERON:0000451	50.50	silver quality
lymph node	UBERON:0000029	47.25	silver quality
primary visual cortex	UBERON:0002436	47.22	silver quality
corpus callosum	UBERON:0002336	45.80	silver quality
superior frontal gyrus	UBERON:0002661	45.32	silver quality
frontal cortex	UBERON:0001870	45.27	silver quality
right hemisphere of cerebellum	UBERON:0014890	44.94	gold quality
cerebral cortex	UBERON:0000956	42.89	silver quality
brain	UBERON:0000955	42.33	silver quality
Brodmann (1909) area 9	UBERON:0013540	41.75	silver quality
anterior cingulate cortex	UBERON:0009835	41.53	gold quality
Ammon’s horn	UBERON:0001954	41.25	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	41.25	silver quality
amygdala	UBERON:0001876	40.43	silver quality
right frontal lobe	UBERON:0002810	39.44	silver quality
putamen	UBERON:0001874	39.25	silver quality
esophagus mucosa	UBERON:0002469	39.24	silver quality
small intestine Peyer’s patch	UBERON:0003454	38.68	silver quality
hypothalamus	UBERON:0001898	38.01	silver quality
pituitary gland	UBERON:0000007	37.59	silver quality
nucleus accumbens	UBERON:0001882	37.55	silver quality
caudate nucleus	UBERON:0001873	37.39	silver quality
substantia nigra	UBERON:0002038	36.17	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.