OPCML-IT2

Summary

OPCML-IT2 (OPCML intronic transcript 2, HGNC:41365) is a long non-coding RNA gene on chromosome 11q25.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41365
Approved symbol	OPCML-IT2
Name	OPCML intronic transcript 2
Location	11q25
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255371
Ensembl biotype	lncRNA
Entrez	100874332
RNAcentral	URS000054A0B2 — lncRNA, 398 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000533260

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000533260 — 2 exons

Exon	Start	End
ENSE00002184381	132859245	132859576
ENSE00002197061	132860012	132860077

Expression profiles

Bgee: expression breadth broad, 57 present calls, max score 76.17.

Top tissues by expression

57 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.17	gold quality
corpus callosum	UBERON:0002336	65.41	gold quality
prefrontal cortex	UBERON:0000451	62.23	gold quality
liver	UBERON:0002107	61.31	silver quality
kidney	UBERON:0002113	60.01	gold quality
primary visual cortex	UBERON:0002436	58.63	gold quality
gastrocnemius	UBERON:0001388	58.36	gold quality
islet of Langerhans	UBERON:0000006	57.54	gold quality
blood	UBERON:0000178	56.91	gold quality
tibial artery	UBERON:0007610	56.61	gold quality
calcaneal tendon	UBERON:0003701	55.00	gold quality
heart	UBERON:0000948	54.24	gold quality
monocyte	CL:0000576	54.04	gold quality
adrenal tissue	UBERON:0018303	53.81	gold quality
right hemisphere of cerebellum	UBERON:0014890	52.61	gold quality
cerebellar cortex	UBERON:0002129	52.18	gold quality
cerebellar hemisphere	UBERON:0002245	52.00	gold quality
intestine	UBERON:0000160	50.59	gold quality
brain	UBERON:0000955	48.14	gold quality
Ammon’s horn	UBERON:0001954	48.08	gold quality
lung	UBERON:0002048	47.83	gold quality
frontal cortex	UBERON:0001870	47.52	gold quality
lower esophagus muscularis layer	UBERON:0035833	47.22	gold quality
putamen	UBERON:0001874	47.01	gold quality
heart left ventricle	UBERON:0002084	46.95	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	46.52	gold quality
cerebral cortex	UBERON:0000956	46.19	gold quality
stomach	UBERON:0000945	45.23	gold quality
Brodmann (1909) area 9	UBERON:0013540	45.15	gold quality
caudate nucleus	UBERON:0001873	44.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.98

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.