OR1D4

Summary

OR1D4 (olfactory receptor family 1 subfamily D member 4, HGNC:8185) is a unprocessed pseudogene on chromosome 17p13.3. Odorant receptor.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional.

Source: NCBI Gene 653166 — RefSeq curated summary.

At a glance

• Gene type: non-coding (transcribed_unprocessed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:8185
Approved symbol	OR1D4
Name	olfactory receptor family 1 subfamily D member 4
Location	17p13.3
Locus type	gene with protein product
Status	Approved
Aliases	OR17-30
Ensembl gene	ENSG00000255095
Ensembl biotype	transcribed_unprocessed_pseudogene
Entrez	653166

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_unprocessed_pseudogene

ENST00000525719

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000525719 — 1 exons

Exon	Start	End
ENSE00002162126	3240676	3241614

Expression profiles

Bgee: expression breadth tissue_specific, 3 present calls, max score 83.16.

Top tissues by expression

117 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.16	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	54.24	gold quality
bone marrow cell	CL:0002092	38.52	gold quality
skeletal muscle tissue	UBERON:0001134	37.29	gold quality
colonic epithelium	UBERON:0000397	37.20	gold quality
ventricular zone	UBERON:0003053	36.48	gold quality
cortical plate	UBERON:0005343	36.47	gold quality
ganglionic eminence	UBERON:0004023	35.49	gold quality
muscle tissue	UBERON:0002385	33.94	gold quality
bone marrow	UBERON:0002371	32.95	gold quality
hindlimb stylopod muscle	UBERON:0004252	32.15	gold quality
stromal cell of endometrium	CL:0002255	29.87	gold quality
monocyte	CL:0000576	29.79	gold quality
leukocyte	CL:0000738	29.59	gold quality
prefrontal cortex	UBERON:0000451	29.44	gold quality
tonsil	UBERON:0002372	29.03	gold quality
liver	UBERON:0002107	29.00	gold quality
blood	UBERON:0000178	28.29	silver quality
duodenum	UBERON:0002114	28.14	gold quality
lymph node	UBERON:0000029	27.57	gold quality
islet of Langerhans	UBERON:0000006	26.55	gold quality
vermiform appendix	UBERON:0001154	26.42	gold quality
gall bladder	UBERON:0002110	25.98	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	25.89	gold quality
placenta	UBERON:0001987	25.81	gold quality
adrenal tissue	UBERON:0018303	25.43	gold quality
primary visual cortex	UBERON:0002436	24.61	gold quality
pancreas	UBERON:0001264	24.58	gold quality
right lobe of liver	UBERON:0001114	24.19	gold quality
superior frontal gyrus	UBERON:0002661	24.08	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.