OR1E3

Summary

OR1E3 (olfactory receptor family 1 subfamily E member 3 (gene/pseudogene), HGNC:8191) is a unprocessed pseudogene on chromosome 17p13.3. Odorant receptor.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome.

Source: NCBI Gene 8389 — RefSeq curated summary.

At a glance

• Gene type: non-coding (unprocessed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:8191
Approved symbol	OR1E3
Name	olfactory receptor family 1 subfamily E member 3 (gene/pseudogene)
Location	17p13.3
Locus type	gene with protein product
Status	Approved
Aliases	OR17-210
Ensembl gene	ENSG00000142163
Ensembl biotype	unprocessed_pseudogene
Entrez	8389

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 unprocessed_pseudogene

ENST00000575608

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000575608 — 1 exons

Exon	Start	End
ENSE00002672845	3116427	3117374

Expression profiles

Bgee: expression breadth tissue_specific, 1 present calls, max score 65.38.

Top tissues by expression

270 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
pancreatic ductal cell	CL:0002079	65.38	silver quality
mucosa of urinary bladder	UBERON:0001259	64.50	gold quality
tibialis anterior	UBERON:0001385	63.56	silver quality
ileal mucosa	UBERON:0000331	63.30	silver quality
gluteal muscle	UBERON:0002000	59.65	gold quality
triceps brachii	UBERON:0001509	59.13	gold quality
cranial nerve II	UBERON:0000941	56.46	silver quality
deltoid	UBERON:0001476	56.24	gold quality
skin of hip	UBERON:0001554	53.44	silver quality
tibia	UBERON:0000979	52.58	gold quality
epithelial cell of pancreas	CL:0000083	52.13	gold quality
decidua	UBERON:0002450	51.40	gold quality
quadriceps femoris	UBERON:0001377	50.92	gold quality
upper arm skin	UBERON:0004263	50.42	gold quality
buccal mucosa cell	CL:0002336	50.28	gold quality
Brodmann (1909) area 46	UBERON:0006483	49.97	gold quality
blood vessel layer	UBERON:0004797	49.29	gold quality
cervix squamous epithelium	UBERON:0006922	49.20	gold quality
hair follicle	UBERON:0002073	49.18	gold quality
vastus lateralis	UBERON:0001379	49.04	gold quality
olfactory bulb	UBERON:0002264	48.92	gold quality
choroid plexus epithelium	UBERON:0003911	48.89	gold quality
myocardium	UBERON:0002349	48.87	gold quality
type B pancreatic cell	CL:0000169	48.83	gold quality
oviduct epithelium	UBERON:0004804	48.65	gold quality
cardiac muscle of right atrium	UBERON:0003379	48.55	gold quality
CA1 field of hippocampus	UBERON:0003881	48.50	gold quality
cervix epithelium	UBERON:0004801	48.39	gold quality
left ventricle myocardium	UBERON:0006566	48.24	gold quality
orbitofrontal cortex	UBERON:0004167	48.20	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.48

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• OR17-201 exhibits specific saturable binding to the pig odorant-binding protein, in contrast to OR17-209 (PMID:12379593)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.