OR2A1-AS1

Summary

OR2A1-AS1 (OR2A1 antisense RNA 1, HGNC:49168) is a long non-coding RNA gene on chromosome 7q35.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49168
Approved symbol	OR2A1-AS1
Name	OR2A1 antisense RNA 1
Location	7q35
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000244479
Ensembl biotype	lncRNA
Entrez	101928492
RNAcentral	URS00007E43CA — lncRNA, 946 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 81 — 81 lncRNA

ENST00000461843, ENST00000462305, ENST00000463561, ENST00000467944, ENST00000468575, ENST00000470435, ENST00000475089, ENST00000476560, ENST00000478806, ENST00000478925, ENST00000479887, ENST00000486094, ENST00000487102, ENST00000488041, ENST00000489488, ENST00000493539, ENST00000496968, ENST00000498397, ENST00000641121, ENST00000836905, ENST00000836906, ENST00000836907, ENST00000837083, ENST00000837084, ENST00000837085, ENST00000837086, ENST00000837087, ENST00000837088, ENST00000837089, ENST00000837389, ENST00000837390, ENST00000837391, ENST00000837392, ENST00000837393, ENST00000837394, ENST00000837395, ENST00000837396, ENST00000837397, ENST00000837398, ENST00000837399, ENST00000837400, ENST00000837401, ENST00000837402, ENST00000837403, ENST00000837404, ENST00000837405, ENST00000837406, ENST00000837407, ENST00000837408, ENST00000837409, ENST00000837410, ENST00000837411, ENST00000837412, ENST00000837413, ENST00000837414, ENST00000837415, ENST00000837416, ENST00000837417, ENST00000837418, ENST00000837419, ENST00000837420, ENST00000837421, ENST00000837422, ENST00000837423, ENST00000837424, ENST00000837425, ENST00000837426, ENST00000837427, ENST00000837428, ENST00000837429, ENST00000837430, ENST00000837431, ENST00000837432, ENST00000837433, ENST00000837434, ENST00000837435, ENST00000837436, ENST00000837437, ENST00000837438, ENST00000837439, ENST00000837440

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000461843 — 3 exons

Exon	Start	End
ENSE00003812288	144343187	144343298
ENSE00004256850	144355338	144355439
ENSE00004256852	144250044	144251610

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 94.10.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0185 / max 11.8839, expressed in 6 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
86688	0.0185	6

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.10	gold quality
colonic epithelium	UBERON:0000397	86.10	gold quality
left lobe of thyroid gland	UBERON:0001120	86.08	gold quality
thyroid gland	UBERON:0002046	85.35	gold quality
right lobe of thyroid gland	UBERON:0001119	83.60	gold quality
granulocyte	CL:0000094	79.63	gold quality
adult mammalian kidney	UBERON:0000082	78.84	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.57	gold quality
sural nerve	UBERON:0015488	77.98	gold quality
cortical plate	UBERON:0005343	77.95	gold quality
bone marrow cell	CL:0002092	77.63	gold quality
thoracic mammary gland	UBERON:0005200	77.63	gold quality
kidney	UBERON:0002113	77.61	gold quality
spleen	UBERON:0002106	77.34	gold quality
tonsil	UBERON:0002372	77.17	gold quality
left ovary	UBERON:0002119	77.14	gold quality
ovary	UBERON:0000992	77.08	gold quality
subcutaneous adipose tissue	UBERON:0002190	76.86	gold quality
ectocervix	UBERON:0012249	76.86	gold quality
adipose tissue	UBERON:0001013	76.85	gold quality
omental fat pad	UBERON:0010414	76.71	gold quality
left uterine tube	UBERON:0001303	76.47	gold quality
right ovary	UBERON:0002118	75.97	gold quality
ventricular zone	UBERON:0003053	75.63	gold quality
metanephros cortex	UBERON:0010533	74.41	gold quality
uterine cervix	UBERON:0000002	74.39	gold quality
bone marrow	UBERON:0002371	73.97	gold quality
upper lobe of left lung	UBERON:0008952	73.89	gold quality
cortex of kidney	UBERON:0001225	73.86	gold quality
descending thoracic aorta	UBERON:0002345	73.74	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.56

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LncRNA OR2A1-AS1 index predicts survival in germinal center-like diffuse large B-cell lymphoma. (PMID:36059090)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.