OR51J1

Summary

OR51J1 (olfactory receptor family 51 subfamily J member 1, HGNC:14856) is a unprocessed pseudogene on chromosome 11p15.4. Odorant receptor.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional.

Source: NCBI Gene 79470 — RefSeq curated summary.

At a glance

• Gene type: non-coding (unprocessed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:14856
Approved symbol	OR51J1
Name	olfactory receptor family 51 subfamily J member 1
Location	11p15.4
Locus type	gene with protein product
Status	Approved
Ensembl gene	ENSG00000184321
Ensembl biotype	unprocessed_pseudogene
Entrez	79470

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 unprocessed_pseudogene

ENST00000332043

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000332043 — 1 exons

Exon	Start	End
ENSE00001319651	5402597	5403547

Expression profiles

Bgee: expression breadth broad, 13 present calls, max score 85.92.

Top tissues by expression

219 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.92	gold quality
tibialis anterior	UBERON:0001385	76.09	silver quality
ileal mucosa	UBERON:0000331	74.57	gold quality
pancreatic ductal cell	CL:0002079	72.96	gold quality
epithelial cell of pancreas	CL:0000083	65.26	silver quality
deltoid	UBERON:0001476	60.50	silver quality
upper leg skin	UBERON:0004262	57.02	gold quality
nasal cavity epithelium	UBERON:0005384	54.86	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
endothelial cell	CL:0000115	54.30	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
myocardium	UBERON:0002349	50.25	gold quality
sural nerve	UBERON:0015488	49.91	gold quality
skin of hip	UBERON:0001554	48.50	silver quality
quadriceps femoris	UBERON:0001377	48.46	gold quality
substantia nigra pars reticulata	UBERON:0001966	46.76	gold quality
colonic epithelium	UBERON:0000397	46.41	gold quality
vastus lateralis	UBERON:0001379	45.69	gold quality
layer of synovial tissue	UBERON:0007616	43.55	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
substantia nigra pars compacta	UBERON:0001965	42.16	gold quality
epithelium of nasopharynx	UBERON:0001951	41.97	gold quality
medial globus pallidus	UBERON:0002477	41.77	gold quality
oviduct epithelium	UBERON:0004804	41.51	gold quality
superficial temporal artery	UBERON:0001614	41.33	gold quality
globus pallidus	UBERON:0001875	41.23	gold quality
inferior vagus X ganglion	UBERON:0005363	41.19	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.98

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Investigation of olfactory receptor family 51 subfamily j member 1 (OR51J1) gene susceptibility as a potential breast cancer-associated biomarker. (PMID:33566867)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.