OVCH1-AS1

Summary

OVCH1-AS1 (OVCH1 antisense RNA 1, HGNC:44484) is a long non-coding RNA gene on chromosome 12p11.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44484
Approved symbol	OVCH1-AS1
Name	OVCH1 antisense RNA 1
Location	12p11.22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000257599
Ensembl biotype	lncRNA
Entrez	101055625
RNAcentral	URS000075D789 — lncRNA, 1294 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000549411, ENST00000550906, ENST00000551108, ENST00000641955, ENST00000701302, ENST00000737458, ENST00000737459, ENST00000737460, ENST00000737461, ENST00000737462, ENST00000737463

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000549411 — 2 exons

Exon	Start	End
ENSE00002364451	29425925	29426064
ENSE00002370091	29486886	29487488

Expression profiles

Bgee: expression breadth ubiquitous, 155 present calls, max score 82.48.

FANTOM5 (CAGE): breadth broad, TPM avg 0.9400 / max 25.5577, expressed in 538 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
124899	0.7202	421
124900	0.1675	80
124898	0.0524	7

Top tissues by expression

248 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	82.48	gold quality
left testis	UBERON:0004533	79.64	gold quality
endothelial cell	CL:0000115	78.42	gold quality
right testis	UBERON:0004534	78.35	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.30	gold quality
testis	UBERON:0000473	77.30	gold quality
pancreatic ductal cell	CL:0002079	75.09	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	73.46	gold quality
bone marrow cell	CL:0002092	72.93	gold quality
colonic epithelium	UBERON:0000397	69.20	gold quality
tendon of biceps brachii	UBERON:0008188	68.75	gold quality
buccal mucosa cell	CL:0002336	68.67	gold quality
leukocyte	CL:0000738	64.91	gold quality
monocyte	CL:0000576	64.55	gold quality
lower esophagus mucosa	UBERON:0035834	63.72	gold quality
ileal mucosa	UBERON:0000331	62.98	gold quality
cortical plate	UBERON:0005343	61.94	gold quality
tendon	UBERON:0000043	61.34	silver quality
vermiform appendix	UBERON:0001154	61.11	gold quality
ventricular zone	UBERON:0003053	59.91	gold quality
lymph node	UBERON:0000029	59.73	gold quality
right coronary artery	UBERON:0001625	59.49	gold quality
blood	UBERON:0000178	59.08	gold quality
granulocyte	CL:0000094	58.51	gold quality
ganglionic eminence	UBERON:0004023	58.04	gold quality
right atrium auricular region	UBERON:0006631	57.88	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.84	gold quality
adult organism	UBERON:0007023	57.74	gold quality
stromal cell of endometrium	CL:0002255	57.48	gold quality
smooth muscle tissue	UBERON:0001135	57.44	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.46

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• OVCH1 Antisense RNA 1 is differentially expressed between non-frail and frail old adults. (PMID:37817005)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.