OXCT1-AS1

Summary

OXCT1-AS1 (OXCT1 antisense RNA 1, HGNC:40423) is a long non-coding RNA gene on chromosome 5p13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40423
Approved symbol	OXCT1-AS1
Name	OXCT1 antisense RNA 1
Location	5p13.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	SARRAH
Ensembl gene	ENSG00000248668
Ensembl biotype	lncRNA
Entrez	100874002
RNAcentral	URS000075B18B — lncRNA, 1731 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 12 lncRNA, 1 retained_intron

ENST00000508458, ENST00000510509, ENST00000651810, ENST00000654321, ENST00000716686, ENST00000791749, ENST00000791750, ENST00000791751, ENST00000791752, ENST00000791753, ENST00000791754, ENST00000791755, ENST00000791756

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000508458 — 3 exons

Exon	Start	End
ENSE00002026243	41870291	41870382
ENSE00002057437	41870766	41872241
ENSE00002078061	41870030	41870192

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 90.87.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.87	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.05	gold quality
heart left ventricle	UBERON:0002084	75.15	gold quality
apex of heart	UBERON:0002098	74.03	gold quality
ventricular zone	UBERON:0003053	73.61	gold quality
sural nerve	UBERON:0015488	73.34	gold quality
heart	UBERON:0000948	72.67	gold quality
hindlimb stylopod muscle	UBERON:0004252	72.46	gold quality
ganglionic eminence	UBERON:0004023	71.80	gold quality
right atrium auricular region	UBERON:0006631	71.71	gold quality
prefrontal cortex	UBERON:0000451	70.75	gold quality
cortical plate	UBERON:0005343	70.71	gold quality
calcaneal tendon	UBERON:0003701	68.78	gold quality
skeletal muscle tissue	UBERON:0001134	67.88	gold quality
superior frontal gyrus	UBERON:0002661	67.51	gold quality
stromal cell of endometrium	CL:0002255	67.17	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	66.96	gold quality
popliteal artery	UBERON:0002250	66.88	gold quality
tibial artery	UBERON:0007610	66.86	gold quality
frontal cortex	UBERON:0001870	66.24	gold quality
muscle of leg	UBERON:0001383	66.19	gold quality
gastrocnemius	UBERON:0001388	66.16	gold quality
substantia nigra	UBERON:0002038	65.76	gold quality
bone marrow	UBERON:0002371	65.58	gold quality
cerebral cortex	UBERON:0000956	64.13	gold quality
temporal lobe	UBERON:0001871	64.12	gold quality
amygdala	UBERON:0001876	64.07	gold quality
lower esophagus muscularis layer	UBERON:0035833	64.06	gold quality
descending thoracic aorta	UBERON:0002345	64.03	gold quality
lower esophagus	UBERON:0013473	63.97	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.12

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• Novel LncRNA OXCT1-AS1 indicates poor prognosis and contributes to tumorigenesis by regulating miR-195/CDC25A axis in glioblastoma. (PMID:33832517)
• lncRNA OXCT1-AS1 Promotes Metastasis in Non-Small-Cell Lung Cancer by Stabilizing LEF1, In Vitro and In Vivo. (PMID:34337014)
• MicroRNA-886 suppresses osteosarcoma cell proliferation and its maturation is suppressed by long non-coding RNA OXCT1-AS1. (PMID:35191809)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.