P3H2-AS1

Summary

P3H2-AS1 (P3H2 antisense RNA 1, HGNC:40886) is a long non-coding RNA gene on chromosome 3q28.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40886
Approved symbol	P3H2-AS1
Name	P3H2 antisense RNA 1
Location	3q28
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225764
Ensembl biotype	lncRNA
Entrez	101929152
RNAcentral	URS0000052DF4 — lncRNA, 730 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000412203, ENST00000685757, ENST00000691942, ENST00000747181, ENST00000747182, ENST00000747183, ENST00000747184, ENST00000747185, ENST00000747186, ENST00000747187, ENST00000747188, ENST00000747189, ENST00000747190, ENST00000747191, ENST00000747192

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412203 — 5 exons

Exon	Start	End
ENSE00001674650	190120964	190121089
ENSE00001732899	190143286	190143501
ENSE00001784544	190144606	190144848
ENSE00001803808	190128929	190129075
ENSE00003885596	190144998	190145107

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 80.93.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4247 / max 62.4545, expressed in 189 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
40547	0.4247	189

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.93	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	73.28	gold quality
ventricular zone	UBERON:0003053	65.59	gold quality
ganglionic eminence	UBERON:0004023	62.56	gold quality
cortical plate	UBERON:0005343	59.01	gold quality
kidney	UBERON:0002113	58.62	gold quality
adult mammalian kidney	UBERON:0000082	58.61	gold quality
prefrontal cortex	UBERON:0000451	58.44	gold quality
metanephros cortex	UBERON:0010533	58.33	gold quality
cortex of kidney	UBERON:0001225	57.65	gold quality
lower esophagus mucosa	UBERON:0035834	57.22	gold quality
superior frontal gyrus	UBERON:0002661	55.96	gold quality
liver	UBERON:0002107	54.67	silver quality
frontal cortex	UBERON:0001870	54.41	gold quality
hindlimb stylopod muscle	UBERON:0004252	54.23	gold quality
hypothalamus	UBERON:0001898	53.90	gold quality
primary visual cortex	UBERON:0002436	53.86	gold quality
spleen	UBERON:0002106	53.62	gold quality
skin of abdomen	UBERON:0001416	53.10	gold quality
zone of skin	UBERON:0000014	52.93	gold quality
skin of leg	UBERON:0001511	52.87	gold quality
placenta	UBERON:0001987	52.80	gold quality
cerebral cortex	UBERON:0000956	52.60	gold quality
lymph node	UBERON:0000029	52.00	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	51.91	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	51.88	gold quality
anterior cingulate cortex	UBERON:0009835	51.57	gold quality
right lung	UBERON:0002167	51.49	gold quality
ectocervix	UBERON:0012249	51.32	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	51.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.40

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.