PACRG-AS3

Summary

PACRG-AS3 (PACRG antisense RNA 3, HGNC:52053) is a long non-coding RNA gene on chromosome 6q26.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52053
Approved symbol	PACRG-AS3
Name	PACRG antisense RNA 3
Location	6q26
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225683
Ensembl biotype	lncRNA
Entrez	729658
RNAcentral	URS000075DF64 — lncRNA, 2204 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 28 — 28 lncRNA

ENST00000419182, ENST00000612841, ENST00000614038, ENST00000620150, ENST00000622071, ENST00000622490, ENST00000653112, ENST00000653943, ENST00000654125, ENST00000654692, ENST00000655388, ENST00000656774, ENST00000658293, ENST00000658885, ENST00000659382, ENST00000660067, ENST00000660683, ENST00000660774, ENST00000661121, ENST00000663456, ENST00000663473, ENST00000664395, ENST00000665860, ENST00000666094, ENST00000666799, ENST00000668978, ENST00000670264, ENST00000671031

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419182 — 3 exons

Exon	Start	End
ENSE00001641032	163190908	163190982
ENSE00001664210	163191602	163191808
ENSE00001749904	163165414	163166262

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 88.46.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4610 / max 94.5977, expressed in 71 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
76582	0.2517	61
76583	0.1784	52
76581	0.0309	20

Top tissues by expression

198 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
C1 segment of cervical spinal cord	UBERON:0006469	88.46	gold quality
spinal cord	UBERON:0002240	86.54	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.26	gold quality
sperm	CL:0000019	84.04	silver quality
corpus callosum	UBERON:0002336	79.10	gold quality
putamen	UBERON:0001874	77.18	gold quality
substantia nigra	UBERON:0002038	76.86	gold quality
midbrain	UBERON:0001891	74.80	gold quality
caudate nucleus	UBERON:0001873	74.03	gold quality
inferior vagus X ganglion	UBERON:0005363	72.95	gold quality
Brodmann (1909) area 46	UBERON:0006483	72.23	gold quality
medial globus pallidus	UBERON:0002477	71.52	gold quality
colonic epithelium	UBERON:0000397	71.41	gold quality
amygdala	UBERON:0001876	70.47	gold quality
Brodmann (1909) area 9	UBERON:0013540	70.45	gold quality
globus pallidus	UBERON:0001875	70.09	gold quality
Ammon’s horn	UBERON:0001954	69.80	gold quality
sural nerve	UBERON:0015488	69.42	gold quality
left ventricle myocardium	UBERON:0006566	69.05	gold quality
hypothalamus	UBERON:0001898	68.52	gold quality
nucleus accumbens	UBERON:0001882	68.13	gold quality
cardiac muscle of right atrium	UBERON:0003379	67.56	gold quality
right frontal lobe	UBERON:0002810	66.70	gold quality
medulla oblongata	UBERON:0001896	66.57	silver quality
primary visual cortex	UBERON:0002436	65.52	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	65.18	gold quality
prefrontal cortex	UBERON:0000451	65.12	gold quality
forebrain	UBERON:0001890	64.85	gold quality
tibial nerve	UBERON:0001323	64.34	gold quality
brain	UBERON:0000955	64.31	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.