PAK4-AS1

Summary

PAK4-AS1 (PAK4 antisense RNA 1, HGNC:58161) is a long non-coding RNA gene.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58161
Approved symbol	PAK4-AS1
Name	PAK4 antisense RNA 1
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC011443.1
Ensembl gene	ENSG00000269172
Ensembl biotype	lncRNA
Entrez	124904714
RNAcentral	URS000046D6B5 — lncRNA, 365 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000599484

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000599484 — 2 exons

Exon	Start	End
ENSE00003048772	39136422	39136463
ENSE00003148888	39134882	39135204

Expression profiles

Bgee: expression breadth broad, 98 present calls, max score 72.44.

Top tissues by expression

98 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	72.44	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.76	gold quality
monocyte	CL:0000576	67.82	gold quality
bone marrow cell	CL:0002092	66.13	silver quality
bone marrow	UBERON:0002371	63.86	gold quality
skeletal muscle tissue	UBERON:0001134	63.76	gold quality
liver	UBERON:0002107	60.95	gold quality
tonsil	UBERON:0002372	59.34	silver quality
islet of Langerhans	UBERON:0000006	58.42	gold quality
blood	UBERON:0000178	57.64	gold quality
left testis	UBERON:0004533	57.03	gold quality
muscle of leg	UBERON:0001383	56.95	gold quality
testis	UBERON:0000473	56.53	gold quality
prefrontal cortex	UBERON:0000451	56.45	gold quality
right testis	UBERON:0004534	54.81	gold quality
gastrocnemius	UBERON:0001388	54.73	gold quality
right coronary artery	UBERON:0001625	54.31	gold quality
adrenal tissue	UBERON:0018303	54.28	gold quality
cortex of kidney	UBERON:0001225	53.84	gold quality
kidney	UBERON:0002113	53.72	gold quality
right lobe of liver	UBERON:0001114	52.83	gold quality
adult mammalian kidney	UBERON:0000082	50.88	gold quality
thoracic mammary gland	UBERON:0005200	50.42	gold quality
body of pancreas	UBERON:0001150	50.02	gold quality
endometrium	UBERON:0001295	49.96	gold quality
heart left ventricle	UBERON:0002084	49.70	gold quality
corpus callosum	UBERON:0002336	49.30	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	48.99	gold quality
tibial artery	UBERON:0007610	48.88	gold quality
adrenal gland	UBERON:0002369	48.82	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.