PAK6-AS1

Summary

PAK6-AS1 (PAK6 antisense RNA 1, HGNC:33868) is a long non-coding RNA gene on chromosome 15q15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33868
Approved symbol	PAK6-AS1
Name	PAK6 antisense RNA 1
Location	15q15.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ38596
Ensembl gene	ENSG00000176753
Ensembl biotype	lncRNA
Entrez	644809
RNAcentral	URS0001BBE386 — lncRNA, 2178 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 1 retained_intron, 1 lncRNA

ENST00000559727, ENST00000623360

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000559727 — 1 exons

Exon	Start	End
ENSE00002538125	40251776	40252969

Expression profiles

Bgee: expression breadth ubiquitous, 125 present calls, max score 79.59.

Top tissues by expression

225 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cardiac muscle of right atrium	UBERON:0003379	79.59	gold quality
left ventricle myocardium	UBERON:0006566	79.08	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.11	silver quality
kidney epithelium	UBERON:0004819	71.84	gold quality
myocardium	UBERON:0002349	70.09	gold quality
cardiac atrium	UBERON:0002081	67.05	gold quality
right atrium auricular region	UBERON:0006631	66.91	gold quality
mucosa of paranasal sinus	UBERON:0005030	66.09	gold quality
right adrenal gland cortex	UBERON:0035827	65.51	gold quality
epithelial cell of pancreas	CL:0000083	64.63	gold quality
left adrenal gland cortex	UBERON:0035825	63.83	gold quality
right adrenal gland	UBERON:0001233	63.38	gold quality
left adrenal gland	UBERON:0001234	63.27	gold quality
epithelium of nasopharynx	UBERON:0001951	63.27	gold quality
adrenal cortex	UBERON:0001235	62.78	gold quality
heart	UBERON:0000948	62.35	gold quality
apex of heart	UBERON:0002098	62.29	gold quality
adrenal gland	UBERON:0002369	62.04	gold quality
left lobe of thyroid gland	UBERON:0001120	61.56	gold quality
right lobe of thyroid gland	UBERON:0001119	61.47	gold quality
heart left ventricle	UBERON:0002084	61.33	gold quality
cardiac ventricle	UBERON:0002082	60.78	gold quality
thyroid gland	UBERON:0002046	60.50	gold quality
cerebellar hemisphere	UBERON:0002245	59.44	gold quality
cerebellar cortex	UBERON:0002129	59.40	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.18	gold quality
cerebellum	UBERON:0002037	58.81	gold quality
right hemisphere of cerebellum	UBERON:0014890	58.36	gold quality
leukocyte	CL:0000738	58.02	silver quality
nasal cavity epithelium	UBERON:0005384	57.79	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.