PALB2-AS1

Summary

PALB2-AS1 (PALB2 antisense RNA 1, HGNC:58305) is a long non-coding RNA gene on chromosome 16p12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58305
Approved symbol	PALB2-AS1
Name	PALB2 antisense RNA 1
Location	16p12.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261723
Ensembl biotype	lncRNA
Entrez	139440216
RNAcentral	URS00005E87E5 — lncRNA, 627 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000561764

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000561764 — 4 exons

Exon	Start	End
ENSE00002576060	23605841	23605956
ENSE00002586984	23607315	23607383
ENSE00002601343	23623900	23624107
ENSE00002620779	23617600	23617833

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 79.19.

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.19	silver quality
sural nerve	UBERON:0015488	70.35	gold quality
ganglionic eminence	UBERON:0004023	63.40	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.52	gold quality
skeletal muscle tissue	UBERON:0001134	58.59	gold quality
monocyte	CL:0000576	56.21	gold quality
lymph node	UBERON:0000029	55.41	gold quality
bone marrow	UBERON:0002371	54.51	silver quality
stromal cell of endometrium	CL:0002255	53.98	silver quality
calcaneal tendon	UBERON:0003701	53.71	silver quality
adrenal tissue	UBERON:0018303	53.35	gold quality
duodenum	UBERON:0002114	52.75	gold quality
blood	UBERON:0000178	52.51	gold quality
islet of Langerhans	UBERON:0000006	52.16	gold quality
muscle tissue	UBERON:0002385	52.08	gold quality
endometrium	UBERON:0001295	52.00	gold quality
apex of heart	UBERON:0002098	51.79	gold quality
prefrontal cortex	UBERON:0000451	51.42	gold quality
muscle of leg	UBERON:0001383	51.07	gold quality
superior frontal gyrus	UBERON:0002661	50.89	gold quality
right coronary artery	UBERON:0001625	50.82	gold quality
vermiform appendix	UBERON:0001154	50.66	gold quality
esophagus mucosa	UBERON:0002469	50.48	gold quality
granulocyte	CL:0000094	50.42	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	50.35	gold quality
rectum	UBERON:0001052	50.29	gold quality
gall bladder	UBERON:0002110	50.14	gold quality
mucosa of transverse colon	UBERON:0004991	50.10	gold quality
right adrenal gland cortex	UBERON:0035827	49.80	gold quality
gastrocnemius	UBERON:0001388	49.73	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.42

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.