PANK1-AS1

Summary

PANK1-AS1 (PANK1 antisense RNA 1, HGNC:55718) is a long non-coding RNA gene on chromosome 10q23.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55718
Approved symbol	PANK1-AS1
Name	PANK1 antisense RNA 1
Location	10q23.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232936
Ensembl biotype	lncRNA
Entrez	105378421
RNAcentral	URS00026A1D42 — lncRNA, 1967 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000451733, ENST00000454174, ENST00000660192, ENST00000777678

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000451733 — 4 exons

Exon	Start	End
ENSE00001721767	89650059	89650231
ENSE00001801126	89648923	89649021
ENSE00004146591	89650553	89650671
ENSE00004146592	89645282	89645499

Expression profiles

Bgee: expression breadth ubiquitous, 106 present calls, max score 73.32.

Top tissues by expression

106 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	73.32	silver quality
colonic epithelium	UBERON:0000397	72.24	gold quality
gall bladder	UBERON:0002110	62.53	gold quality
ganglionic eminence	UBERON:0004023	61.25	gold quality
primary visual cortex	UBERON:0002436	58.95	gold quality
liver	UBERON:0002107	58.30	gold quality
lymph node	UBERON:0000029	58.01	gold quality
tonsil	UBERON:0002372	56.95	silver quality
duodenum	UBERON:0002114	56.39	gold quality
right lobe of liver	UBERON:0001114	55.93	gold quality
islet of Langerhans	UBERON:0000006	55.16	gold quality
cortex of kidney	UBERON:0001225	54.60	gold quality
kidney	UBERON:0002113	54.35	gold quality
monocyte	CL:0000576	53.77	gold quality
bone marrow	UBERON:0002371	53.59	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.33	gold quality
blood	UBERON:0000178	53.20	gold quality
adult mammalian kidney	UBERON:0000082	52.61	gold quality
muscle of leg	UBERON:0001383	52.34	gold quality
gastrocnemius	UBERON:0001388	51.60	gold quality
prefrontal cortex	UBERON:0000451	51.03	gold quality
metanephros cortex	UBERON:0010533	50.89	gold quality
skeletal muscle tissue	UBERON:0001134	50.70	silver quality
heart left ventricle	UBERON:0002084	50.11	gold quality
heart	UBERON:0000948	48.94	gold quality
corpus callosum	UBERON:0002336	48.60	silver quality
right lobe of thyroid gland	UBERON:0001119	48.22	gold quality
cerebellar cortex	UBERON:0002129	47.88	silver quality
cerebellum	UBERON:0002037	47.82	silver quality
cerebellar hemisphere	UBERON:0002245	47.82	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.14

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.