PAPLN-AS1

Summary

PAPLN-AS1 (PAPLN antisense RNA 1, HGNC:55451) is a long non-coding RNA gene on chromosome 14q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55451
Approved symbol	PAPLN-AS1
Name	PAPLN antisense RNA 1
Location	14q24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258376
Ensembl biotype	lncRNA
Entrez	101928123
RNAcentral	URS0000A76B3B — lncRNA, 1735 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000554614

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000554614 — 2 exons

Exon	Start	End
ENSE00004049814	73242651	73245244
ENSE00004049815	73245524	73246018

Expression profiles

Bgee: expression breadth ubiquitous, 143 present calls, max score 84.30.

FANTOM5 (CAGE): breadth broad, TPM avg 0.9460 / max 48.3036, expressed in 561 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
143957	0.9460	561

Top tissues by expression

222 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
vena cava	UBERON:0004087	84.30	silver quality
bone marrow cell	CL:0002092	75.46	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	74.51	gold quality
superficial temporal artery	UBERON:0001614	73.14	gold quality
lateral globus pallidus	UBERON:0002476	72.70	silver quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	72.49	silver quality
cardia of stomach	UBERON:0001162	72.41	gold quality
ventral tegmental area	UBERON:0002691	72.34	gold quality
pons	UBERON:0000988	72.07	gold quality
saphenous vein	UBERON:0007318	71.71	silver quality
pharyngeal mucosa	UBERON:0000355	71.68	gold quality
body of tongue	UBERON:0011876	71.53	gold quality
pericardium	UBERON:0002407	71.24	silver quality
substantia nigra pars reticulata	UBERON:0001966	71.16	gold quality
nipple	UBERON:0002030	70.95	gold quality
inferior vagus X ganglion	UBERON:0005363	70.92	gold quality
cerebellar vermis	UBERON:0004720	70.89	silver quality
thymus	UBERON:0002370	70.79	gold quality
tongue	UBERON:0001723	70.78	gold quality
corpus callosum	UBERON:0002336	70.54	gold quality
superior surface of tongue	UBERON:0007371	70.46	gold quality
trachea	UBERON:0003126	70.39	gold quality
lateral nuclear group of thalamus	UBERON:0002736	70.16	gold quality
substantia nigra pars compacta	UBERON:0001965	70.14	gold quality
sural nerve	UBERON:0015488	70.01	gold quality
medulla oblongata	UBERON:0001896	69.94	gold quality
pylorus	UBERON:0001166	69.90	gold quality
quadriceps femoris	UBERON:0001377	69.85	gold quality
vastus lateralis	UBERON:0001379	69.74	gold quality
myocardium	UBERON:0002349	69.74	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.36

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.