PAPLN-AS2

Summary

PAPLN-AS2 (PAPLN antisense RNA 2, HGNC:58463) is a long non-coding RNA gene on chromosome 14q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58463
Approved symbol	PAPLN-AS2
Name	PAPLN antisense RNA 2
Location	14q24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258944
Ensembl biotype	lncRNA
Entrez	141858819

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000556578

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000556578 — 3 exons

Exon	Start	End
ENSE00002498082	73272182	73272708
ENSE00002505471	73273939	73274081
ENSE00002532941	73272802	73272908

Expression profiles

Bgee: expression breadth ubiquitous, 158 present calls, max score 90.38.

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	90.38	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.03	silver quality
sural nerve	UBERON:0015488	77.68	gold quality
colonic epithelium	UBERON:0000397	76.21	gold quality
monocyte	CL:0000576	72.82	gold quality
bone marrow cell	CL:0002092	72.65	silver quality
leukocyte	CL:0000738	71.94	gold quality
tibial nerve	UBERON:0001323	71.34	gold quality
metanephros cortex	UBERON:0010533	69.33	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	67.70	gold quality
right lung	UBERON:0002167	67.67	gold quality
right lobe of thyroid gland	UBERON:0001119	66.83	gold quality
small intestine Peyer’s patch	UBERON:0003454	66.54	gold quality
spleen	UBERON:0002106	66.37	gold quality
blood	UBERON:0000178	66.35	gold quality
lower esophagus mucosa	UBERON:0035834	66.02	gold quality
granulocyte	CL:0000094	66.00	gold quality
left lobe of thyroid gland	UBERON:0001120	65.86	gold quality
adenohypophysis	UBERON:0002196	65.46	gold quality
left uterine tube	UBERON:0001303	65.35	gold quality
thyroid gland	UBERON:0002046	65.09	gold quality
cortex of kidney	UBERON:0001225	64.86	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	64.59	gold quality
small intestine	UBERON:0002108	64.03	gold quality
body of uterus	UBERON:0009853	63.84	gold quality
mucosa of stomach	UBERON:0001199	63.63	gold quality
upper lobe of left lung	UBERON:0008952	63.55	gold quality
cortical plate	UBERON:0005343	63.28	gold quality
skin of abdomen	UBERON:0001416	62.92	gold quality
ganglionic eminence	UBERON:0004023	62.87	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.57

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.