PARAIL

Summary

PARAIL (palmitic acid regulated anti-inflammatory lncRNA, HGNC:55545) is a long non-coding RNA gene on chromosome 8q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55545
Approved symbol	PARAIL
Name	palmitic acid regulated anti-inflammatory lncRNA
Location	8q21.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AF117829.1
Ensembl gene	ENSG00000251136
Ensembl biotype	lncRNA
Entrez	101929709
RNAcentral	URS00007E4793 — lncRNA, 1601 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 144 — 144 lncRNA

ENST00000504145, ENST00000519655, ENST00000519854, ENST00000520306, ENST00000521996, ENST00000523859, ENST00000523995, ENST00000524166, ENST00000524190, ENST00000621883, ENST00000653574, ENST00000655144, ENST00000656898, ENST00000658265, ENST00000658477, ENST00000661105, ENST00000669938, ENST00000685145, ENST00000685448, ENST00000685619, ENST00000685787, ENST00000685988, ENST00000686009, ENST00000686147, ENST00000686537, ENST00000687204, ENST00000687824, ENST00000688654, ENST00000688669, ENST00000688855, ENST00000689241, ENST00000690564, ENST00000691313, ENST00000691446, ENST00000691595, ENST00000691897, ENST00000692782, ENST00000693018, ENST00000701257, ENST00000701802, ENST00000701998, ENST00000814452, ENST00000814453, ENST00000814454, ENST00000814455, ENST00000814456, ENST00000814457, ENST00000814458, ENST00000814459, ENST00000814460, ENST00000814461, ENST00000814462, ENST00000814463, ENST00000814464, ENST00000814465, ENST00000814466, ENST00000814467, ENST00000814468, ENST00000814469, ENST00000814470, ENST00000814471, ENST00000814472, ENST00000814473, ENST00000814474, ENST00000814475, ENST00000814476, ENST00000814477, ENST00000814478, ENST00000814479, ENST00000814480, ENST00000814481, ENST00000814482, ENST00000814483, ENST00000814484, ENST00000814485, ENST00000814486, ENST00000814487, ENST00000814488, ENST00000814489, ENST00000814490, ENST00000814491, ENST00000814492, ENST00000814493, ENST00000814494, ENST00000814495, ENST00000814496, ENST00000814497, ENST00000814498, ENST00000814499, ENST00000814500, ENST00000814501, ENST00000814502, ENST00000814503, ENST00000814504, ENST00000814505, ENST00000814506, ENST00000814507, ENST00000814508, ENST00000814509, ENST00000814510, ENST00000814511, ENST00000814512, ENST00000814513, ENST00000814514, ENST00000814515, ENST00000814516, ENST00000814517, ENST00000814518, ENST00000814519, ENST00000814520, ENST00000814521, ENST00000814522, ENST00000814523, ENST00000814524, ENST00000814525, ENST00000814526, ENST00000814527, ENST00000814528, ENST00000814529, ENST00000814530, ENST00000814531, ENST00000814532, ENST00000814533, ENST00000814534, ENST00000814535, ENST00000814536, ENST00000814537, ENST00000814538, ENST00000814539, ENST00000814540, ENST00000814541, ENST00000814542, ENST00000814543, ENST00000814544, ENST00000814545, ENST00000814546, ENST00000814547, ENST00000814548, ENST00000814549, ENST00000814550, ENST00000814551, ENST00000814552, ENST00000814553, ENST00000814554

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504145 — 5 exons

Exon	Start	End
ENSE00002053997	89722015	89722156
ENSE00004215556	89725518	89725641
ENSE00004215557	89757045	89757711
ENSE00004215585	89717395	89717728
ENSE00004215620	89724629	89724966

Expression profiles

Bgee: expression breadth ubiquitous, 167 present calls, max score 93.15.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 7.3222 / max 262.6677, expressed in 1700 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
93859	4.3465	1543
93860	1.7120	980
93857	0.9326	347
93858	0.3310	171

Top tissues by expression

251 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
calcaneal tendon	UBERON:0003701	93.15	gold quality
sural nerve	UBERON:0015488	89.41	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.20	gold quality
colonic epithelium	UBERON:0000397	87.57	gold quality
bone marrow cell	CL:0002092	86.62	gold quality
gall bladder	UBERON:0002110	86.15	gold quality
left lobe of thyroid gland	UBERON:0001120	85.34	gold quality
right uterine tube	UBERON:0001302	85.15	gold quality
adenohypophysis	UBERON:0002196	84.16	gold quality
right lobe of thyroid gland	UBERON:0001119	83.92	gold quality
thyroid gland	UBERON:0002046	83.83	gold quality
left ovary	UBERON:0002119	83.64	gold quality
endocervix	UBERON:0000458	83.34	gold quality
minor salivary gland	UBERON:0001830	83.18	gold quality
right ovary	UBERON:0002118	83.16	gold quality
tibial artery	UBERON:0007610	83.03	gold quality
popliteal artery	UBERON:0002250	83.02	gold quality
body of pancreas	UBERON:0001150	82.98	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	82.85	gold quality
tibial nerve	UBERON:0001323	82.69	gold quality
body of uterus	UBERON:0009853	82.62	gold quality
muscle layer of sigmoid colon	UBERON:0035805	82.47	gold quality
aorta	UBERON:0000947	82.14	gold quality
right lobe of liver	UBERON:0001114	82.08	gold quality
ectocervix	UBERON:0012249	82.08	gold quality
left uterine tube	UBERON:0001303	82.00	gold quality
lower esophagus muscularis layer	UBERON:0035833	81.93	gold quality
lower esophagus	UBERON:0013473	81.92	gold quality
right atrium auricular region	UBERON:0006631	81.90	gold quality
adrenal tissue	UBERON:0018303	81.75	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.79

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LOC101929709 promotes gastric cancer progression by aiding LIN28B to stabilize c-MYC mRNA. (PMID:36284068)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.