PARP11-AS1

Summary

PARP11-AS1 (PARP11 antisense RNA 1, HGNC:40103) is a long non-coding RNA gene on chromosome 12p13.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40103
Approved symbol	PARP11-AS1
Name	PARP11 antisense RNA 1
Location	12p13.32
Locus type	RNA, long non-coding
Status	Approved
Aliases	lncAPAT
Ensembl gene	ENSG00000256862
Ensembl biotype	lncRNA
Entrez	105369609
RNAcentral	URS00026A2343 — lncRNA, 2284 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000537149, ENST00000545163, ENST00000545357, ENST00000649371, ENST00000654573, ENST00000663241, ENST00000668261, ENST00000813516, ENST00000813517, ENST00000813518

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000537149 — 2 exons

Exon	Start	End
ENSE00004213657	3909884	3910385
ENSE00004213665	3871542	3871956

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 90.49.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4360 / max 53.0413, expressed in 63 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
123503	0.3428	57
123502	0.0878	33
123501	0.0054	2

Top tissues by expression

251 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.49	gold quality
sperm	CL:0000019	89.36	gold quality
buccal mucosa cell	CL:0002336	88.18	silver quality
right testis	UBERON:0004534	85.46	gold quality
left testis	UBERON:0004533	85.25	gold quality
testis	UBERON:0000473	82.56	gold quality
pancreatic ductal cell	CL:0002079	80.28	silver quality
granulocyte	CL:0000094	76.30	gold quality
blood	UBERON:0000178	73.39	gold quality
lymph node	UBERON:0000029	72.39	gold quality
bone marrow cell	CL:0002092	71.99	silver quality
sural nerve	UBERON:0015488	71.13	gold quality
colonic epithelium	UBERON:0000397	70.69	silver quality
kidney epithelium	UBERON:0004819	69.66	gold quality
ventricular zone	UBERON:0003053	68.82	gold quality
vermiform appendix	UBERON:0001154	66.24	gold quality
calcaneal tendon	UBERON:0003701	66.09	gold quality
adrenal tissue	UBERON:0018303	65.07	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	64.74	gold quality
tonsil	UBERON:0002372	63.83	gold quality
upper arm skin	UBERON:0004263	62.55	gold quality
caecum	UBERON:0001153	61.88	gold quality
bone marrow	UBERON:0002371	61.53	gold quality
cortical plate	UBERON:0005343	61.37	gold quality
leukocyte	CL:0000738	61.36	gold quality
right uterine tube	UBERON:0001302	60.79	gold quality
ganglionic eminence	UBERON:0004023	60.76	gold quality
adult organism	UBERON:0007023	60.25	silver quality
ileal mucosa	UBERON:0000331	60.09	silver quality
monocyte	CL:0000576	59.22	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.15

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.