PBX1-AS1

Summary

PBX1-AS1 (PBX1 antisense RNA 1, HGNC:40425) is a long non-coding RNA gene on chromosome 1q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40425
Approved symbol	PBX1-AS1
Name	PBX1 antisense RNA 1
Location	1q23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233693
Ensembl biotype	lncRNA
Entrez	100505795
RNAcentral	URS0000608F58 — lncRNA, 1963 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000421530

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000421530 — 4 exons

Exon	Start	End
ENSE00001598262	164769859	164770116
ENSE00001660331	164774429	164774641
ENSE00001668673	164769116	164769356
ENSE00001797818	164770327	164771577

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 82.03.

Top tissues by expression

80 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.03	gold quality
colonic epithelium	UBERON:0000397	75.68	gold quality
bone marrow cell	CL:0002092	72.72	silver quality
skeletal muscle tissue	UBERON:0001134	72.69	gold quality
urinary bladder	UBERON:0001255	71.39	gold quality
tonsil	UBERON:0002372	65.84	silver quality
hindlimb stylopod muscle	UBERON:0004252	62.07	gold quality
small intestine	UBERON:0002108	61.72	silver quality
adrenal tissue	UBERON:0018303	61.06	gold quality
stomach	UBERON:0000945	59.18	gold quality
kidney	UBERON:0002113	58.08	gold quality
thoracic mammary gland	UBERON:0005200	56.67	silver quality
adrenal gland	UBERON:0002369	55.92	gold quality
prefrontal cortex	UBERON:0000451	55.49	gold quality
lung	UBERON:0002048	55.46	gold quality
thyroid gland	UBERON:0002046	54.06	silver quality
corpus callosum	UBERON:0002336	52.76	gold quality
intestine	UBERON:0000160	52.11	gold quality
calcaneal tendon	UBERON:0003701	51.66	silver quality
uterine cervix	UBERON:0000002	50.60	gold quality
adult mammalian kidney	UBERON:0000082	50.41	gold quality
cortex of kidney	UBERON:0001225	50.38	silver quality
prostate gland	UBERON:0002367	49.34	silver quality
multicellular organism	UBERON:0000468	48.94	gold quality
endometrium	UBERON:0001295	48.69	gold quality
muscle of leg	UBERON:0001383	48.45	gold quality
ovary	UBERON:0000992	47.87	silver quality
heart	UBERON:0000948	47.85	gold quality
primary visual cortex	UBERON:0002436	47.60	silver quality
brain	UBERON:0000955	47.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.05

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.