PBX3-DT

Summary

PBX3-DT (PBX3 divergent transcript, HGNC:24638) is a long non-coding RNA gene on chromosome 9q33.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:24638
Approved symbol	PBX3-DT
Name	PBX3 divergent transcript
Location	9q33.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229582
Ensembl biotype	lncRNA
Entrez	51145
RNAcentral	URS000075E8DF — lncRNA, 712 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 6 lncRNA, 1 retained_intron

ENST00000444800, ENST00000606827, ENST00000614664, ENST00000812393, ENST00000812394, ENST00000812395, ENST00000812396

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000444800 — 2 exons

Exon	Start	End
ENSE00004211382	125743750	125743937
ENSE00004211383	125745416	125746133

Expression profiles

Bgee: expression breadth ubiquitous, 103 present calls, max score 72.31.

Top tissues by expression

231 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	72.31	silver quality
buccal mucosa cell	CL:0002336	67.99	gold quality
ganglionic eminence	UBERON:0004023	66.42	gold quality
tongue squamous epithelium	UBERON:0006919	65.57	gold quality
left testis	UBERON:0004533	64.03	gold quality
right testis	UBERON:0004534	63.01	gold quality
testis	UBERON:0000473	61.88	gold quality
diaphragm	UBERON:0001103	61.02	gold quality
ventricular zone	UBERON:0003053	60.04	gold quality
cortical plate	UBERON:0005343	60.01	silver quality
mononuclear cell	CL:0000842	55.66	gold quality
monocyte	CL:0000576	55.41	gold quality
kidney epithelium	UBERON:0004819	55.14	gold quality
tibialis anterior	UBERON:0001385	54.82	silver quality
ileal mucosa	UBERON:0000331	54.49	silver quality
gall bladder	UBERON:0002110	53.03	gold quality
left ventricle myocardium	UBERON:0006566	51.80	gold quality
prefrontal cortex	UBERON:0000451	50.87	gold quality
gastrocnemius	UBERON:0001388	50.74	gold quality
right lobe of liver	UBERON:0001114	50.60	gold quality
Brodmann (1909) area 46	UBERON:0006483	50.11	gold quality
quadriceps femoris	UBERON:0001377	49.88	gold quality
bone marrow cell	CL:0002092	49.58	gold quality
uterine cervix	UBERON:0000002	49.47	gold quality
myocardium	UBERON:0002349	49.47	gold quality
cervix squamous epithelium	UBERON:0006922	49.20	gold quality
pancreas	UBERON:0001264	49.19	silver quality
hair follicle	UBERON:0002073	49.18	gold quality
cardiac muscle of right atrium	UBERON:0003379	49.14	gold quality
embryo	UBERON:0000922	49.05	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.