PCDH10-DT

Summary

PCDH10-DT (PCDH10 divergent transcript, HGNC:53036) is a long non-coding RNA gene on chromosome 4q28.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53036
Approved symbol	PCDH10-DT
Name	PCDH10 divergent transcript
Location	4q28.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250241
Ensembl biotype	lncRNA
Entrez	101927359
RNAcentral	URS00007E48C3 — lncRNA, 2841 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 42 — 42 lncRNA

ENST00000505289, ENST00000506897, ENST00000509715, ENST00000656167, ENST00000659189, ENST00000660426, ENST00000662896, ENST00000664075, ENST00000664880, ENST00000665360, ENST00000667505, ENST00000670166, ENST00000670280, ENST00000671428, ENST00000691466, ENST00000732794, ENST00000732795, ENST00000732796, ENST00000732797, ENST00000732798, ENST00000732799, ENST00000732800, ENST00000732801, ENST00000732802, ENST00000732803, ENST00000732804, ENST00000732805, ENST00000732806, ENST00000732807, ENST00000732808, ENST00000732809, ENST00000732810, ENST00000732811, ENST00000732812, ENST00000732813, ENST00000732814, ENST00000732815, ENST00000732816, ENST00000732817, ENST00000732818, ENST00000732819, ENST00000732820

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000505289 — 8 exons

Exon	Start	End
ENSE00002027443	133145604	133145745
ENSE00002030192	133142711	133142782
ENSE00002031185	133147199	133147276
ENSE00002054829	133139826	133139881
ENSE00002057137	133093790	133095950
ENSE00002062572	133096736	133096883
ENSE00002077114	133138960	133139033
ENSE00003879770	133149029	133149114

Expression profiles

Bgee: expression breadth ubiquitous, 145 present calls, max score 81.63.

Top tissues by expression

220 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.63	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.90	gold quality
corpus callosum	UBERON:0002336	74.45	gold quality
sural nerve	UBERON:0015488	74.31	gold quality
prefrontal cortex	UBERON:0000451	73.27	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	71.21	gold quality
hypothalamus	UBERON:0001898	71.18	gold quality
nucleus accumbens	UBERON:0001882	71.02	gold quality
anterior cingulate cortex	UBERON:0009835	70.59	gold quality
caudate nucleus	UBERON:0001873	70.54	gold quality
Brodmann (1909) area 9	UBERON:0013540	70.54	gold quality
putamen	UBERON:0001874	70.13	gold quality
substantia nigra	UBERON:0002038	69.89	gold quality
amygdala	UBERON:0001876	69.63	gold quality
right frontal lobe	UBERON:0002810	68.99	gold quality
spinal cord	UBERON:0002240	68.41	gold quality
stromal cell of endometrium	CL:0002255	68.40	gold quality
neocortex	UBERON:0001950	67.52	gold quality
ascending aorta	UBERON:0001496	67.40	gold quality
frontal cortex	UBERON:0001870	67.40	gold quality
midbrain	UBERON:0001891	67.19	gold quality
thoracic aorta	UBERON:0001515	67.17	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	66.88	gold quality
descending thoracic aorta	UBERON:0002345	65.42	gold quality
cerebral cortex	UBERON:0000956	64.76	gold quality
forebrain	UBERON:0001890	64.33	gold quality
cortical plate	UBERON:0005343	63.26	gold quality
Ammon’s horn	UBERON:0001954	63.00	gold quality
brain	UBERON:0000955	62.57	gold quality
aorta	UBERON:0000947	62.16	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.73

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.