PCNA-AS1

Summary

PCNA-AS1 (PCNA antisense RNA 1, HGNC:37184) is a long non-coding RNA gene on chromosome 20p12.3.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:37184
Approved symbol	PCNA-AS1
Name	PCNA antisense RNA 1
Location	20p12.3
Locus type	RNA, long non-coding
Status	Approved
Entrez	100302739
RNAcentral	URS000075EA0B — lncRNA, 384 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000651339 (20:5119922 GACA>G), RS1002678053 (20:5119407 G>A,C), RS1003823567 (20:5118131 T>C), RS1005680917 (20:5120203 G>A), RS1006865078 (20:5119722 G>A,C), RS1006923552 (20:5118983 A>G), RS1007928143 (20:5120070 C>T), RS1007960729 (20:5120196 G>A,C), RS1008565872 (20:5118474 G>A), RS1008951017 (20:5118288 A>C,G), RS1011591386 (20:5119462 A>G), RS1012190868 (20:5120005 A>C,G,T), RS1012571389 (20:5119899 G>A), RS1012613373 (20:5119386 G>A), RS1012709232 (20:5119076 C>T)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

3 total (human), top 3 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Cisplatin	affects cotreatment, increases expression	2
jinfukang	affects cotreatment, increases expression	1
Smoke	decreases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.