PCOLCE-AS1

Summary

PCOLCE-AS1 (PCOLCE antisense RNA 1, HGNC:40430) is a long non-coding RNA gene on chromosome 7q22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40430
Approved symbol	PCOLCE-AS1
Name	PCOLCE antisense RNA 1
Location	7q22.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224729
Ensembl biotype	lncRNA
Entrez	100129845
RNAcentral	URS000075AF6D — lncRNA, 2550 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000442166, ENST00000446022, ENST00000653812, ENST00000739653, ENST00000739654

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000442166 — 9 exons

Exon	Start	End
ENSE00001601371	100601620	100601683
ENSE00001669987	100603838	100604038
ENSE00001683813	100602340	100603166
ENSE00001848151	100592825	100593074
ENSE00001863038	100599671	100599802
ENSE00001888643	100600040	100600189
ENSE00001901481	100590230	100590331
ENSE00001941480	100589402	100590082
ENSE00003549939	100600723	100600852

Expression profiles

Bgee: expression breadth ubiquitous, 153 present calls, max score 86.79.

FANTOM5 (CAGE): breadth broad, TPM avg 1.3477 / max 25.2641, expressed in 661 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
85223	0.4806	263
85221	0.4372	206
85220	0.2344	145
85222	0.1152	35
85219	0.0803	33

Top tissues by expression

239 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.79	gold quality
colonic epithelium	UBERON:0000397	74.36	gold quality
stromal cell of endometrium	CL:0002255	71.92	gold quality
left ovary	UBERON:0002119	71.54	gold quality
right testis	UBERON:0004534	70.96	gold quality
left testis	UBERON:0004533	70.57	gold quality
sural nerve	UBERON:0015488	70.37	gold quality
tibial nerve	UBERON:0001323	70.10	gold quality
right ovary	UBERON:0002118	69.56	gold quality
endocervix	UBERON:0000458	69.43	gold quality
right uterine tube	UBERON:0001302	69.40	gold quality
body of uterus	UBERON:0009853	69.10	gold quality
sperm	CL:0000019	68.82	silver quality
ectocervix	UBERON:0012249	68.56	gold quality
testis	UBERON:0000473	68.18	gold quality
ovary	UBERON:0000992	66.15	gold quality
cortical plate	UBERON:0005343	65.62	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	65.39	gold quality
bone marrow cell	CL:0002092	65.24	silver quality
uterine cervix	UBERON:0000002	65.20	gold quality
right hemisphere of cerebellum	UBERON:0014890	65.03	gold quality
cerebellar hemisphere	UBERON:0002245	64.93	gold quality
cerebellar cortex	UBERON:0002129	64.80	gold quality
left uterine tube	UBERON:0001303	64.50	gold quality
metanephros cortex	UBERON:0010533	63.82	gold quality
cerebellum	UBERON:0002037	63.18	gold quality
right coronary artery	UBERON:0001625	62.49	gold quality
ganglionic eminence	UBERON:0004023	62.03	gold quality
lower esophagus muscularis layer	UBERON:0035833	61.95	gold quality
lower esophagus	UBERON:0013473	61.86	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	2341.07
E-ANND-3	yes	10.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.