PCYT1B-AS1

Summary

PCYT1B-AS1 (PCYT1B antisense RNA 1, HGNC:40431) is a long non-coding RNA gene on chromosome Xp22.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40431
Approved symbol	PCYT1B-AS1
Name	PCYT1B antisense RNA 1
Location	Xp22.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236836
Ensembl biotype	lncRNA
Entrez	100874088
RNAcentral	URS000001FF4F — lncRNA, 275 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000432626

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000432626 — 2 exons

Exon	Start	End
ENSE00001633314	24650073	24650149
ENSE00001684434	24658040	24658237

Expression profiles

Bgee: expression breadth broad, 43 present calls, max score 76.39.

Top tissues by expression

43 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.39	gold quality
corpus callosum	UBERON:0002336	74.62	gold quality
heart left ventricle	UBERON:0002084	66.79	gold quality
tibial artery	UBERON:0007610	65.86	gold quality
vermiform appendix	UBERON:0001154	65.63	gold quality
monocyte	CL:0000576	63.94	gold quality
gastrocnemius	UBERON:0001388	60.81	gold quality
blood	UBERON:0000178	60.13	gold quality
muscle layer of sigmoid colon	UBERON:0035805	59.92	gold quality
prostate gland	UBERON:0002367	58.66	gold quality
Brodmann (1909) area 9	UBERON:0013540	57.11	gold quality
endometrium	UBERON:0001295	55.71	silver quality
amygdala	UBERON:0001876	55.41	gold quality
fundus of stomach	UBERON:0001160	55.21	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	55.12	gold quality
urinary bladder	UBERON:0001255	54.83	gold quality
body of pancreas	UBERON:0001150	54.41	gold quality
right atrium auricular region	UBERON:0006631	54.18	gold quality
transverse colon	UBERON:0001157	53.94	gold quality
esophagus mucosa	UBERON:0002469	51.02	gold quality
substantia nigra	UBERON:0002038	49.82	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	49.81	gold quality
Ammon’s horn	UBERON:0001954	49.30	gold quality
lower esophagus muscularis layer	UBERON:0035833	48.90	gold quality
left adrenal gland	UBERON:0001234	48.49	gold quality
right hemisphere of cerebellum	UBERON:0014890	48.25	gold quality
putamen	UBERON:0001874	48.17	gold quality
tibial nerve	UBERON:0001323	47.61	gold quality
left coronary artery	UBERON:0001626	47.61	gold quality
cerebellar hemisphere	UBERON:0002245	47.52	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.