PDE11A-AS1

Summary

PDE11A-AS1 (PDE11A antisense RNA 1, HGNC:40433) is a long non-coding RNA gene on chromosome 2q31.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40433
Approved symbol	PDE11A-AS1
Name	PDE11A antisense RNA 1
Location	2q31.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229941
Ensembl biotype	lncRNA
Entrez	105373764
RNAcentral	URS0000A76FAD — lncRNA, 845 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000412133, ENST00000450227, ENST00000653062, ENST00000815670, ENST00000815671

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412133 — 4 exons

Exon	Start	End
ENSE00001645839	177702488	177702749
ENSE00001662409	177701094	177701228
ENSE00001732706	177698429	177698571
ENSE00001737520	177723089	177723289

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 86.29.

Top tissues by expression

221 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.29	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.47	silver quality
corpus epididymis	UBERON:0004359	64.86	gold quality
tibialis anterior	UBERON:0001385	64.44	silver quality
hindlimb stylopod muscle	UBERON:0004252	64.29	gold quality
ileal mucosa	UBERON:0000331	62.37	gold quality
ganglionic eminence	UBERON:0004023	62.08	gold quality
monocyte	CL:0000576	61.06	gold quality
pancreatic ductal cell	CL:0002079	59.02	silver quality
adult mammalian kidney	UBERON:0000082	58.32	gold quality
gall bladder	UBERON:0002110	56.86	gold quality
kidney epithelium	UBERON:0004819	55.13	gold quality
metanephros cortex	UBERON:0010533	54.95	gold quality
cortex of kidney	UBERON:0001225	54.79	gold quality
right lobe of liver	UBERON:0001114	54.62	gold quality
epithelial cell of pancreas	CL:0000083	54.53	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.11	gold quality
kidney	UBERON:0002113	53.78	gold quality
deltoid	UBERON:0001476	53.66	gold quality
smooth muscle tissue	UBERON:0001135	53.54	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
muscle of leg	UBERON:0001383	52.90	gold quality
cerebellar vermis	UBERON:0004720	52.80	gold quality
gastrocnemius	UBERON:0001388	52.59	gold quality
rectum	UBERON:0001052	51.77	gold quality
metanephros	UBERON:0000081	51.41	gold quality
islet of Langerhans	UBERON:0000006	50.70	gold quality
myocardium	UBERON:0002349	50.25	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.