PDE2A-AS1

Summary

PDE2A-AS1 (PDE2A antisense RNA 1, HGNC:40435) is a long non-coding RNA gene on chromosome 11q13.4.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40435
Approved symbol	PDE2A-AS1
Name	PDE2A antisense RNA 1
Location	11q13.4
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255808
Ensembl biotype	lncRNA
Entrez	105369379
RNAcentral	URS0000453745 — lncRNA, 562 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000540912

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000540912 — 4 exons

Exon	Start	End
ENSE00002209751	72643237	72643518
ENSE00002250272	72649250	72649338
ENSE00002290357	72659359	72659407
ENSE00002295482	72658069	72658210

Expression profiles

Bgee: expression breadth broad, 66 present calls, max score 63.09.

Top tissues by expression

66 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	63.09	silver quality
right adrenal gland cortex	UBERON:0035827	57.59	gold quality
bone marrow	UBERON:0002371	57.08	gold quality
monocyte	CL:0000576	52.99	gold quality
blood	UBERON:0000178	52.85	silver quality
prefrontal cortex	UBERON:0000451	51.98	gold quality
calcaneal tendon	UBERON:0003701	51.82	silver quality
small intestine	UBERON:0002108	51.74	gold quality
tibial nerve	UBERON:0001323	48.64	silver quality
adrenal tissue	UBERON:0018303	48.31	silver quality
primary visual cortex	UBERON:0002436	47.61	silver quality
endometrium	UBERON:0001295	47.59	silver quality
gastrocnemius	UBERON:0001388	47.04	gold quality
superior frontal gyrus	UBERON:0002661	46.52	silver quality
heart left ventricle	UBERON:0002084	46.20	gold quality
frontal cortex	UBERON:0001870	45.31	gold quality
putamen	UBERON:0001874	45.17	gold quality
body of uterus	UBERON:0009853	44.64	gold quality
adrenal gland	UBERON:0002369	44.47	gold quality
Brodmann (1909) area 9	UBERON:0013540	43.99	gold quality
tibial artery	UBERON:0007610	43.91	silver quality
liver	UBERON:0002107	43.48	silver quality
left coronary artery	UBERON:0001626	43.38	silver quality
Ammon’s horn	UBERON:0001954	43.22	gold quality
cerebral cortex	UBERON:0000956	43.11	gold quality
brain	UBERON:0000955	42.72	gold quality
amygdala	UBERON:0001876	42.55	silver quality
nucleus accumbens	UBERON:0001882	42.53	gold quality
caudate nucleus	UBERON:0001873	42.37	gold quality
subcutaneous adipose tissue	UBERON:0002190	42.14	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.