PDE2A-AS2

Summary

PDE2A-AS2 (PDE2A antisense RNA 2, HGNC:40434) is a long non-coding RNA gene on chromosome 11q13.4.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40434
Approved symbol	PDE2A-AS2
Name	PDE2A antisense RNA 2
Location	11q13.4
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256633
Ensembl biotype	lncRNA
Entrez	105369378
RNAcentral	URS0002A18998 — lncRNA, 959 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000545254

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000545254 — 2 exons

Exon	Start	End
ENSE00004232690	72584509	72585056
ENSE00004232691	72587801	72588211

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 86.87.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1847 / max 10.7371, expressed in 74 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
115748	0.1847	74

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	86.87	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.38	silver quality
granulocyte	CL:0000094	77.83	gold quality
spleen	UBERON:0002106	75.24	gold quality
blood	UBERON:0000178	73.14	gold quality
subcutaneous adipose tissue	UBERON:0002190	69.59	gold quality
lymph node	UBERON:0000029	68.75	gold quality
adipose tissue	UBERON:0001013	68.53	gold quality
omental fat pad	UBERON:0010414	67.39	gold quality
sural nerve	UBERON:0015488	66.84	gold quality
leukocyte	CL:0000738	66.44	gold quality
vermiform appendix	UBERON:0001154	65.76	gold quality
tonsil	UBERON:0002372	65.75	gold quality
monocyte	CL:0000576	65.56	gold quality
bone marrow	UBERON:0002371	65.26	gold quality
ventricular zone	UBERON:0003053	64.14	gold quality
myometrium	UBERON:0001296	63.08	gold quality
superior frontal gyrus	UBERON:0002661	62.87	gold quality
thoracic mammary gland	UBERON:0005200	62.65	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.83	gold quality
gall bladder	UBERON:0002110	60.48	gold quality
smooth muscle tissue	UBERON:0001135	60.42	gold quality
right atrium auricular region	UBERON:0006631	60.27	gold quality
ganglionic eminence	UBERON:0004023	60.19	gold quality
gastrocnemius	UBERON:0001388	59.90	gold quality
muscle of leg	UBERON:0001383	59.75	gold quality
lower esophagus mucosa	UBERON:0035834	59.61	gold quality
cortical plate	UBERON:0005343	58.99	gold quality
right adrenal gland	UBERON:0001233	58.94	gold quality
right frontal lobe	UBERON:0002810	58.94	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.61

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.