PDE3A-AS1

Summary

PDE3A-AS1 (PDE3A antisense RNA 1, HGNC:40436) is a long non-coding RNA gene on chromosome 12p12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40436
Approved symbol	PDE3A-AS1
Name	PDE3A antisense RNA 1
Location	12p12.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256879
Ensembl biotype	lncRNA
Entrez	120766147
RNAcentral	URS00026A1BEB — lncRNA, 3076 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000535755, ENST00000745828

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000535755 — 2 exons

Exon	Start	End
ENSE00002260680	20361732	20361834
ENSE00002287679	20369841	20370262

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 80.19.

Top tissues by expression

122 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	80.19	gold quality
placenta	UBERON:0001987	70.77	gold quality
sural nerve	UBERON:0015488	68.14	gold quality
ganglionic eminence	UBERON:0004023	66.53	gold quality
gall bladder	UBERON:0002110	66.43	gold quality
cortical plate	UBERON:0005343	66.26	gold quality
tonsil	UBERON:0002372	64.72	gold quality
duodenum	UBERON:0002114	63.55	gold quality
vermiform appendix	UBERON:0001154	62.24	gold quality
fallopian tube	UBERON:0003889	61.94	gold quality
skeletal muscle tissue	UBERON:0001134	61.70	gold quality
mucosa of stomach	UBERON:0001199	60.89	gold quality
heart left ventricle	UBERON:0002084	59.91	gold quality
islet of Langerhans	UBERON:0000006	59.90	gold quality
heart	UBERON:0000948	58.69	gold quality
popliteal artery	UBERON:0002250	58.65	gold quality
tibial artery	UBERON:0007610	58.57	gold quality
right uterine tube	UBERON:0001302	58.48	gold quality
urinary bladder	UBERON:0001255	57.97	gold quality
prefrontal cortex	UBERON:0000451	57.57	gold quality
liver	UBERON:0002107	57.49	gold quality
smooth muscle tissue	UBERON:0001135	57.17	gold quality
bone marrow	UBERON:0002371	57.09	gold quality
stomach	UBERON:0000945	56.32	gold quality
calcaneal tendon	UBERON:0003701	56.19	gold quality
monocyte	CL:0000576	55.84	gold quality
ascending aorta	UBERON:0001496	55.67	gold quality
thoracic aorta	UBERON:0001515	55.48	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.18	gold quality
left coronary artery	UBERON:0001626	55.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.