PDE4B-AS1

Summary

PDE4B-AS1 (PDE4B antisense RNA 1, HGNC:40437) is a long non-coding RNA gene on chromosome 1p31.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40437
Approved symbol	PDE4B-AS1
Name	PDE4B antisense RNA 1
Location	1p31.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227466
Ensembl biotype	lncRNA
Entrez	101927139
RNAcentral	URS00001F2C5D — lncRNA, 456 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000424138

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424138 — 3 exons

Exon	Start	End
ENSE00001647931	66046226	66046261
ENSE00001714717	66050531	66050718
ENSE00001792600	66042500	66042731

Expression profiles

Bgee: expression breadth broad, 65 present calls, max score 97.76.

Top tissues by expression

65 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	97.76	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.63	silver quality
tonsil	UBERON:0002372	77.76	gold quality
colonic epithelium	UBERON:0000397	70.36	gold quality
primary visual cortex	UBERON:0002436	62.13	gold quality
adrenal tissue	UBERON:0018303	57.14	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.39	gold quality
liver	UBERON:0002107	55.84	gold quality
prefrontal cortex	UBERON:0000451	55.82	gold quality
monocyte	CL:0000576	54.74	gold quality
placenta	UBERON:0001987	54.51	gold quality
thoracic mammary gland	UBERON:0005200	53.24	gold quality
blood	UBERON:0000178	52.31	gold quality
superior frontal gyrus	UBERON:0002661	52.24	gold quality
stomach	UBERON:0000945	49.69	gold quality
tibial artery	UBERON:0007610	48.68	gold quality
ascending aorta	UBERON:0001496	48.21	gold quality
cerebellar cortex	UBERON:0002129	48.05	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	47.99	gold quality
gastrocnemius	UBERON:0001388	47.92	gold quality
kidney	UBERON:0002113	47.92	silver quality
right atrium auricular region	UBERON:0006631	47.56	gold quality
cerebellar hemisphere	UBERON:0002245	47.40	silver quality
substantia nigra	UBERON:0002038	47.16	gold quality
brain	UBERON:0000955	47.10	gold quality
Ammon’s horn	UBERON:0001954	46.87	gold quality
heart	UBERON:0000948	46.74	silver quality
intestine	UBERON:0000160	46.63	gold quality
heart left ventricle	UBERON:0002084	46.44	silver quality
esophagus mucosa	UBERON:0002469	46.42	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.