PDE4D-AS1

Summary

PDE4D-AS1 (PDE4D antisense RNA 1, HGNC:58182) is a long non-coding RNA gene on chromosome 5q11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58182
Approved symbol	PDE4D-AS1
Name	PDE4D antisense RNA 1
Location	5q11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000247345
Ensembl biotype	lncRNA
Entrez	139281640
RNAcentral	URS0002A6D4E1 — lncRNA, 736 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000500224, ENST00000746044

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000500224 — 2 exons

Exon	Start	End
ENSE00004086566	59063085	59063510
ENSE00004086568	59039761	59040070

Expression profiles

Bgee: expression breadth ubiquitous, 109 present calls, max score 68.85.

Top tissues by expression

109 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue	UBERON:0001134	68.85	gold quality
monocyte	CL:0000576	68.64	gold quality
leukocyte	CL:0000738	67.72	gold quality
cortical plate	UBERON:0005343	65.19	gold quality
muscle tissue	UBERON:0002385	65.14	gold quality
liver	UBERON:0002107	63.65	silver quality
bone marrow cell	CL:0002092	61.82	silver quality
gastrocnemius	UBERON:0001388	57.02	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.02	gold quality
muscle of leg	UBERON:0001383	56.98	gold quality
placenta	UBERON:0001987	56.15	gold quality
bone marrow	UBERON:0002371	55.96	gold quality
blood	UBERON:0000178	55.95	gold quality
calcaneal tendon	UBERON:0003701	55.07	silver quality
apex of heart	UBERON:0002098	53.97	gold quality
urinary bladder	UBERON:0001255	53.69	gold quality
lymph node	UBERON:0000029	53.31	gold quality
islet of Langerhans	UBERON:0000006	52.81	gold quality
prefrontal cortex	UBERON:0000451	52.70	gold quality
myometrium	UBERON:0001296	51.73	gold quality
left adrenal gland	UBERON:0001234	51.52	gold quality
pancreas	UBERON:0001264	51.21	gold quality
granulocyte	CL:0000094	50.77	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	50.77	silver quality
rectum	UBERON:0001052	50.62	gold quality
adrenal gland	UBERON:0002369	50.38	gold quality
gall bladder	UBERON:0002110	50.22	gold quality
left adrenal gland cortex	UBERON:0035825	49.29	gold quality
vermiform appendix	UBERON:0001154	49.27	gold quality
popliteal artery	UBERON:0002250	49.23	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.