PDE7B-AS1

Summary

PDE7B-AS1 (PDE7B antisense RNA 1, HGNC:56334) is a long non-coding RNA gene on chromosome 6q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56334
Approved symbol	PDE7B-AS1
Name	PDE7B antisense RNA 1
Location	6q23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237596
Ensembl biotype	lncRNA
Entrez	644135
RNAcentral	URS0000BC440B — lncRNA, 1586 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 18 — 18 lncRNA

ENST00000413745, ENST00000417643, ENST00000419926, ENST00000576956, ENST00000585946, ENST00000591521, ENST00000615571, ENST00000616427, ENST00000618969, ENST00000625353, ENST00000626130, ENST00000626414, ENST00000626605, ENST00000626816, ENST00000629837, ENST00000655618, ENST00000808454, ENST00000808455

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000413745 — 3 exons

Exon	Start	End
ENSE00001608530	136047309	136047484
ENSE00001775115	136064381	136064638
ENSE00001777920	136044464	136044927

Expression profiles

Bgee: expression breadth ubiquitous, 152 present calls, max score 86.72.

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	86.72	gold quality
right atrium auricular region	UBERON:0006631	84.62	gold quality
cardiac atrium	UBERON:0002081	83.50	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.14	gold quality
colonic epithelium	UBERON:0000397	81.62	gold quality
calcaneal tendon	UBERON:0003701	80.86	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	74.54	gold quality
heart	UBERON:0000948	69.77	gold quality
corpus callosum	UBERON:0002336	68.78	gold quality
metanephros cortex	UBERON:0010533	68.19	gold quality
heart left ventricle	UBERON:0002084	67.09	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	66.64	gold quality
apex of heart	UBERON:0002098	66.35	gold quality
cardiac ventricle	UBERON:0002082	66.18	gold quality
tonsil	UBERON:0002372	65.68	gold quality
left ovary	UBERON:0002119	65.64	gold quality
tendon	UBERON:0000043	65.56	gold quality
bone marrow cell	CL:0002092	64.71	silver quality
ectocervix	UBERON:0012249	64.58	gold quality
right lobe of liver	UBERON:0001114	63.80	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.08	gold quality
ventricular zone	UBERON:0003053	62.93	gold quality
stromal cell of endometrium	CL:0002255	62.63	gold quality
cortical plate	UBERON:0005343	61.29	silver quality
right ovary	UBERON:0002118	61.09	gold quality
ovary	UBERON:0000992	60.89	gold quality
adenohypophysis	UBERON:0002196	60.38	gold quality
upper lobe of left lung	UBERON:0008952	60.25	gold quality
liver	UBERON:0002107	60.07	gold quality
metanephros	UBERON:0000081	59.97	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	6.43

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long non-coding RNA LOC644135 is a potential prognostic indicator in cytogenetically normal acute myeloid leukemia. (PMID:35713000)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.