PDE9A-AS1

Summary

PDE9A-AS1 (PDE9A antisense RNA 1, HGNC:40440) is a long non-coding RNA gene on chromosome 21q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40440
Approved symbol	PDE9A-AS1
Name	PDE9A antisense RNA 1
Location	21q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225731
Ensembl biotype	lncRNA
Entrez	101928284
RNAcentral	URS00026A2897 — lncRNA, 1754 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000437426, ENST00000750647

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000437426 — 2 exons

Exon	Start	End
ENSE00004095166	42741094	42741820
ENSE00004095169	42733593	42734682

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 78.30.

Top tissues by expression

211 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.30	gold quality
mucosa of transverse colon	UBERON:0004991	75.07	gold quality
sural nerve	UBERON:0015488	69.36	gold quality
tibia	UBERON:0000979	62.05	gold quality
colonic epithelium	UBERON:0000397	61.10	silver quality
ventricular zone	UBERON:0003053	59.51	silver quality
nasal cavity epithelium	UBERON:0005384	58.53	gold quality
cortical plate	UBERON:0005343	58.37	silver quality
apex of heart	UBERON:0002098	58.29	gold quality
calcaneal tendon	UBERON:0003701	57.51	gold quality
transverse colon	UBERON:0001157	55.80	gold quality
parietal pleura	UBERON:0002400	55.67	gold quality
omental fat pad	UBERON:0010414	55.62	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.60	gold quality
peritoneum	UBERON:0002358	55.57	gold quality
visceral pleura	UBERON:0002401	55.10	gold quality
small intestine Peyer’s patch	UBERON:0003454	54.95	gold quality
adipose tissue of abdominal region	UBERON:0007808	54.87	gold quality
ganglionic eminence	UBERON:0004023	54.07	silver quality
small intestine	UBERON:0002108	54.03	gold quality
smooth muscle tissue	UBERON:0001135	53.73	gold quality
rectum	UBERON:0001052	53.41	gold quality
heart left ventricle	UBERON:0002084	53.18	gold quality
cardiac ventricle	UBERON:0002082	52.69	gold quality
parotid gland	UBERON:0001831	52.60	gold quality
prefrontal cortex	UBERON:0000451	52.50	gold quality
adipose tissue	UBERON:0001013	51.88	gold quality
muscle of leg	UBERON:0001383	51.74	gold quality
biceps brachii	UBERON:0001507	51.08	gold quality
intestine	UBERON:0000160	50.91	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.