PDGFA-DT

Summary

PDGFA-DT (PDGFA divergent transcript, HGNC:55865) is a long non-coding RNA gene on chromosome 7p22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55865
Approved symbol	PDGFA-DT
Name	PDGFA divergent transcript
Location	7p22.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	HRAT92
Ensembl gene	ENSG00000223855
Ensembl biotype	lncRNA
Entrez	441307
RNAcentral	URS0000314D59 — lncRNA, 3506 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 30 — 30 lncRNA

ENST00000452622, ENST00000656962, ENST00000662957, ENST00000663680, ENST00000688093, ENST00000689546, ENST00000689970, ENST00000690212, ENST00000702988, ENST00000797634, ENST00000797635, ENST00000797636, ENST00000797637, ENST00000797638, ENST00000797639, ENST00000797640, ENST00000797641, ENST00000797642, ENST00000797643, ENST00000797644, ENST00000797645, ENST00000797646, ENST00000797647, ENST00000797648, ENST00000797649, ENST00000797650, ENST00000797651, ENST00000797652, ENST00000797653, ENST00000797654

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000452622 — 3 exons

Exon	Start	End
ENSE00001605704	524080	524280
ENSE00001766188	520391	523316
ENSE00001769206	524854	525232

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 90.97.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3678 / max 45.7408, expressed in 78 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
76855	0.2351	55
76854	0.0844	36
76853	0.0483	18

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right atrium auricular region	UBERON:0006631	90.97	gold quality
monocyte	CL:0000576	90.80	gold quality
apex of heart	UBERON:0002098	89.83	gold quality
leukocyte	CL:0000738	89.44	gold quality
heart left ventricle	UBERON:0002084	86.82	gold quality
heart	UBERON:0000948	86.69	gold quality
ascending aorta	UBERON:0001496	80.81	gold quality
right uterine tube	UBERON:0001302	80.47	gold quality
right coronary artery	UBERON:0001625	80.43	gold quality
thoracic aorta	UBERON:0001515	80.41	gold quality
descending thoracic aorta	UBERON:0002345	78.81	gold quality
granulocyte	CL:0000094	75.08	gold quality
left coronary artery	UBERON:0001626	74.66	gold quality
sural nerve	UBERON:0015488	74.32	gold quality
tibial artery	UBERON:0007610	72.43	gold quality
popliteal artery	UBERON:0002250	72.40	gold quality
right hemisphere of cerebellum	UBERON:0014890	72.06	gold quality
blood	UBERON:0000178	70.63	gold quality
pituitary gland	UBERON:0000007	70.32	gold quality
body of pancreas	UBERON:0001150	70.24	gold quality
cerebellar hemisphere	UBERON:0002245	69.57	gold quality
cerebellar cortex	UBERON:0002129	69.43	gold quality
adenohypophysis	UBERON:0002196	69.36	gold quality
cerebellum	UBERON:0002037	69.35	gold quality
myometrium	UBERON:0001296	68.45	gold quality
right lung	UBERON:0002167	68.40	gold quality
pancreas	UBERON:0001264	68.33	gold quality
right frontal lobe	UBERON:0002810	68.32	gold quality
spleen	UBERON:0002106	68.16	gold quality
Brodmann (1909) area 9	UBERON:0013540	68.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.15

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.