PDGFDDN

Summary

PDGFDDN (PDGFD downstream neighbor, HGNC:56909) is a long non-coding RNA gene on chromosome 11q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56909
Approved symbol	PDGFDDN
Name	PDGFD downstream neighbor
Location	11q22.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AP002989.1
Ensembl gene	ENSG00000254987
Ensembl biotype	lncRNA
Entrez	105369464
RNAcentral	URS0002A4465B — lncRNA, 1293 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000533459, ENST00000812819, ENST00000812820, ENST00000812821, ENST00000812822, ENST00000812823, ENST00000812824, ENST00000812825

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000533459 — 5 exons

Exon	Start	End
ENSE00002158494	103704754	103704898
ENSE00002173550	103680234	103680342
ENSE00002183609	103675994	103676174
ENSE00002189403	103893875	103893953
ENSE00002201713	103895224	103895271

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 81.29.

Top tissues by expression

105 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.29	silver quality
sural nerve	UBERON:0015488	73.35	gold quality
stromal cell of endometrium	CL:0002255	71.40	gold quality
ventricular zone	UBERON:0003053	65.26	gold quality
subcutaneous adipose tissue	UBERON:0002190	60.21	gold quality
colonic epithelium	UBERON:0000397	59.37	silver quality
pancreas	UBERON:0001264	59.00	gold quality
islet of Langerhans	UBERON:0000006	58.86	gold quality
adipose tissue	UBERON:0001013	58.75	gold quality
body of pancreas	UBERON:0001150	58.74	gold quality
placenta	UBERON:0001987	57.90	gold quality
lymph node	UBERON:0000029	57.84	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	57.33	gold quality
omental fat pad	UBERON:0010414	56.82	gold quality
monocyte	CL:0000576	56.03	gold quality
ascending aorta	UBERON:0001496	54.99	gold quality
thoracic aorta	UBERON:0001515	54.28	gold quality
fundus of stomach	UBERON:0001160	53.69	gold quality
endometrium	UBERON:0001295	53.55	gold quality
prefrontal cortex	UBERON:0000451	53.47	gold quality
bone marrow	UBERON:0002371	53.46	gold quality
left adrenal gland	UBERON:0001234	52.97	gold quality
adult mammalian kidney	UBERON:0000082	52.92	gold quality
myometrium	UBERON:0001296	52.89	gold quality
adrenal gland	UBERON:0002369	52.80	gold quality
thoracic mammary gland	UBERON:0005200	52.46	gold quality
vermiform appendix	UBERON:0001154	52.39	gold quality
left coronary artery	UBERON:0001626	52.36	gold quality
right adrenal gland cortex	UBERON:0035827	52.30	gold quality
tibial artery	UBERON:0007610	52.19	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.10

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.