PDK2-AS1

Summary

PDK2-AS1 (PDK2 antisense RNA 1, HGNC:58250) is a long non-coding RNA gene on chromosome 17q21.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58250
Approved symbol	PDK2-AS1
Name	PDK2 antisense RNA 1
Location	17q21.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250282
Ensembl biotype	lncRNA
Entrez	124904026
RNAcentral	URS0000130183 — lncRNA, 430 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000511361

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000511361 — 2 exons

Exon	Start	End
ENSE00002049197	50100704	50101065
ENSE00002057975	50101853	50101920

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 76.96.

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	76.96	gold quality
skeletal muscle tissue	UBERON:0001134	75.78	gold quality
muscle of leg	UBERON:0001383	75.15	gold quality
gastrocnemius	UBERON:0001388	74.27	gold quality
hindlimb stylopod muscle	UBERON:0004252	72.96	gold quality
cerebellar hemisphere	UBERON:0002245	69.10	gold quality
right hemisphere of cerebellum	UBERON:0014890	68.86	gold quality
cerebellar cortex	UBERON:0002129	68.79	gold quality
cerebellum	UBERON:0002037	68.71	gold quality
rectum	UBERON:0001052	67.92	gold quality
ganglionic eminence	UBERON:0004023	67.07	gold quality
apex of heart	UBERON:0002098	66.67	gold quality
liver	UBERON:0002107	66.28	gold quality
duodenum	UBERON:0002114	66.01	gold quality
gall bladder	UBERON:0002110	65.26	gold quality
bone marrow cell	CL:0002092	64.22	silver quality
cortical plate	UBERON:0005343	64.20	gold quality
heart left ventricle	UBERON:0002084	64.05	gold quality
tonsil	UBERON:0002372	64.04	gold quality
right lobe of liver	UBERON:0001114	63.13	gold quality
right adrenal gland cortex	UBERON:0035827	62.76	gold quality
colonic epithelium	UBERON:0000397	62.26	silver quality
left adrenal gland cortex	UBERON:0035825	62.26	gold quality
smooth muscle tissue	UBERON:0001135	61.82	gold quality
heart	UBERON:0000948	61.64	gold quality
right adrenal gland	UBERON:0001233	61.19	gold quality
adrenal gland	UBERON:0002369	60.93	gold quality
left adrenal gland	UBERON:0001234	60.83	gold quality
mucosa of transverse colon	UBERON:0004991	60.56	gold quality
small intestine	UBERON:0002108	60.42	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.94

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.