PDK4-AS1

Summary

PDK4-AS1 (PDK4 antisense RNA 1, HGNC:55767) is a long non-coding RNA gene on chromosome 7q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55767
Approved symbol	PDK4-AS1
Name	PDK4 antisense RNA 1
Location	7q21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231170
Ensembl biotype	lncRNA
Entrez	107986824
RNAcentral	URS0000EF6A29 — lncRNA, 2118 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 27 — 27 lncRNA

ENST00000411728, ENST00000416502, ENST00000432265, ENST00000651203, ENST00000653592, ENST00000656676, ENST00000662949, ENST00000663696, ENST00000665332, ENST00000666870, ENST00000667350, ENST00000668366, ENST00000668636, ENST00000668637, ENST00000669019, ENST00000669024, ENST00000837345, ENST00000837346, ENST00000837347, ENST00000837348, ENST00000837349, ENST00000837350, ENST00000837351, ENST00000837352, ENST00000837353, ENST00000837354, ENST00000837355

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000411728 — 3 exons

Exon	Start	End
ENSE00003848538	95609588	95609862
ENSE00004257734	95609088	95609243
ENSE00004257735	95613051	95613541

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 83.41.

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	83.41	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.43	gold quality
sural nerve	UBERON:0015488	80.68	gold quality
right adrenal gland cortex	UBERON:0035827	80.22	gold quality
monocyte	CL:0000576	79.91	gold quality
right adrenal gland	UBERON:0001233	79.77	gold quality
left adrenal gland	UBERON:0001234	79.52	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.15	gold quality
left adrenal gland cortex	UBERON:0035825	78.94	gold quality
leukocyte	CL:0000738	78.75	gold quality
adrenal gland	UBERON:0002369	78.70	gold quality
gastrocnemius	UBERON:0001388	78.37	gold quality
muscle of leg	UBERON:0001383	76.63	gold quality
hindlimb stylopod muscle	UBERON:0004252	76.48	gold quality
corpus callosum	UBERON:0002336	75.32	gold quality
left ovary	UBERON:0002119	74.62	gold quality
ovary	UBERON:0000992	73.72	gold quality
right ovary	UBERON:0002118	72.35	gold quality
pancreas	UBERON:0001264	72.12	gold quality
islet of Langerhans	UBERON:0000006	72.08	gold quality
body of pancreas	UBERON:0001150	72.03	gold quality
pituitary gland	UBERON:0000007	71.94	gold quality
skeletal muscle tissue	UBERON:0001134	71.56	gold quality
calcaneal tendon	UBERON:0003701	71.30	gold quality
adenohypophysis	UBERON:0002196	70.73	gold quality
heart left ventricle	UBERON:0002084	70.26	gold quality
right atrium auricular region	UBERON:0006631	70.14	gold quality
muscle tissue	UBERON:0002385	70.08	gold quality
adult mammalian kidney	UBERON:0000082	69.86	gold quality
heart	UBERON:0000948	69.78	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.