PDXP-DT

Summary

PDXP-DT (PDXP divergent transcript, HGNC:40525) is a long non-coding RNA gene on chromosome 22q13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40525
Approved symbol	PDXP-DT
Name	PDXP divergent transcript
Location	22q13.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233360
Ensembl biotype	lncRNA
Entrez	101927051
RNAcentral	URS00003D5F5D — lncRNA, 1945 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000456099, ENST00000839909

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000456099 — 6 exons

Exon	Start	End
ENSE00001632459	37643627	37643761
ENSE00001666181	37649854	37649925
ENSE00001712910	37648323	37648422
ENSE00001724364	37658255	37658377
ENSE00001764042	37641832	37642964
ENSE00001781710	37650331	37650712

Expression profiles

Bgee: expression breadth broad, 95 present calls, max score 84.25.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3124 / max 54.1666, expressed in 115 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
194077	0.3124	115

Top tissues by expression

225 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.25	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	77.74	gold quality
biceps brachii	UBERON:0001507	77.53	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	76.75	gold quality
heart right ventricle	UBERON:0002080	74.71	gold quality
endothelial cell	CL:0000115	72.93	gold quality
skeletal muscle tissue	UBERON:0001134	70.88	gold quality
type B pancreatic cell	CL:0000169	70.72	gold quality
gingiva	UBERON:0001828	70.69	gold quality
gingival epithelium	UBERON:0001949	70.66	gold quality
myocardium	UBERON:0002349	70.66	gold quality
tongue squamous epithelium	UBERON:0006919	70.49	gold quality
cervix squamous epithelium	UBERON:0006922	70.48	gold quality
olfactory bulb	UBERON:0002264	69.80	gold quality
vastus lateralis	UBERON:0001379	69.45	gold quality
diaphragm	UBERON:0001103	69.25	gold quality
triceps brachii	UBERON:0001509	69.14	gold quality
inferior olivary complex	UBERON:0002127	68.54	gold quality
dorsal motor nucleus of vagus nerve	UBERON:0002870	68.48	gold quality
quadriceps femoris	UBERON:0001377	68.16	gold quality
cartilage tissue	UBERON:0002418	68.11	gold quality
periodontal ligament	UBERON:0008266	68.11	gold quality
buccal mucosa cell	CL:0002336	67.96	silver quality
decidua	UBERON:0002450	67.88	gold quality
male germ cell	CL:0000015	67.57	gold quality
squamous epithelium	UBERON:0006914	67.54	gold quality
granulocyte	CL:0000094	67.41	gold quality
sperm	CL:0000019	67.19	gold quality
cervix epithelium	UBERON:0004801	67.13	gold quality
gluteal muscle	UBERON:0002000	67.00	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.