PDYN-AS1

Summary

PDYN-AS1 (PDYN antisense RNA 1, HGNC:53462) is a long non-coding RNA gene on chromosome 20p13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53462
Approved symbol	PDYN-AS1
Name	PDYN antisense RNA 1
Location	20p13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233896
Ensembl biotype	lncRNA
Entrez	727993
RNAcentral	URS0000A765C7 — lncRNA, 1838 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000446562, ENST00000651021

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000446562 — 4 exons

Exon	Start	End
ENSE00001600285	1947246	1947651
ENSE00001615886	2006932	2007517
ENSE00001634034	1951479	1951548
ENSE00001758612	1965604	1966343

Expression profiles

Bgee: expression breadth broad, 53 present calls, max score 64.34.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.8451 / max 121.2720, expressed in 101 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
183132	0.6675	91
183133	0.0861	30
183131	0.0630	30
208971	0.0284	17

Top tissues by expression

53 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	64.34	gold quality
bone marrow cell	CL:0002092	62.69	silver quality
monocyte	CL:0000576	60.06	gold quality
colonic epithelium	UBERON:0000397	59.37	silver quality
skin of leg	UBERON:0001511	55.62	gold quality
stomach	UBERON:0000945	54.89	silver quality
urinary bladder	UBERON:0001255	53.57	silver quality
bone marrow	UBERON:0002371	52.98	silver quality
vermiform appendix	UBERON:0001154	52.07	gold quality
prefrontal cortex	UBERON:0000451	51.55	gold quality
cerebellum	UBERON:0002037	51.50	gold quality
cerebellar cortex	UBERON:0002129	51.39	gold quality
blood	UBERON:0000178	51.25	silver quality
cerebellar hemisphere	UBERON:0002245	51.23	gold quality
right hemisphere of cerebellum	UBERON:0014890	50.83	gold quality
brain	UBERON:0000955	48.69	silver quality
muscle of leg	UBERON:0001383	46.89	gold quality
heart	UBERON:0000948	46.17	silver quality
placenta	UBERON:0001987	45.19	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	44.84	gold quality
hindlimb stylopod muscle	UBERON:0004252	44.48	silver quality
adult mammalian kidney	UBERON:0000082	44.35	silver quality
kidney	UBERON:0002113	44.27	silver quality
gastrocnemius	UBERON:0001388	43.82	silver quality
Brodmann (1909) area 9	UBERON:0013540	43.68	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	43.13	silver quality
tibial artery	UBERON:0007610	43.09	silver quality
ovary	UBERON:0000992	43.02	silver quality
subcutaneous adipose tissue	UBERON:0002190	42.54	silver quality
cortex of kidney	UBERON:0001225	42.26	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.09

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.