PEA15-AS1

Summary

PEA15-AS1 (PEA15 antisense RNA 1, HGNC:58221) is a long non-coding RNA gene on chromosome 1q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58221
Approved symbol	PEA15-AS1
Name	PEA15 antisense RNA 1
Location	1q23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227741
Ensembl biotype	lncRNA
Entrez	729867
RNAcentral	URS00005569E9 — lncRNA, 1578 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000418602, ENST00000756717, ENST00000756718

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000418602 — 5 exons

Exon	Start	End
ENSE00001608981	160208257	160208387
ENSE00001651921	160205071	160205134
ENSE00001795254	160208844	160208869
ENSE00004106995	160205338	160206376
ENSE00004106999	160202198	160202516

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 83.53.

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.53	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.41	gold quality
sural nerve	UBERON:0015488	73.42	gold quality
superior frontal gyrus	UBERON:0002661	72.17	gold quality
bone marrow cell	CL:0002092	66.71	silver quality
right testis	UBERON:0004534	64.94	gold quality
bone marrow	UBERON:0002371	64.73	gold quality
left testis	UBERON:0004533	64.48	gold quality
ventricular zone	UBERON:0003053	64.03	gold quality
testis	UBERON:0000473	63.91	gold quality
primary visual cortex	UBERON:0002436	63.64	gold quality
stromal cell of endometrium	CL:0002255	63.20	gold quality
cortical plate	UBERON:0005343	62.28	gold quality
ganglionic eminence	UBERON:0004023	62.00	gold quality
skeletal muscle tissue	UBERON:0001134	61.81	gold quality
granulocyte	CL:0000094	61.30	gold quality
right lobe of liver	UBERON:0001114	61.29	gold quality
right hemisphere of cerebellum	UBERON:0014890	61.16	gold quality
cerebellum	UBERON:0002037	60.99	gold quality
cerebellar cortex	UBERON:0002129	60.77	gold quality
monocyte	CL:0000576	60.52	gold quality
cerebellar hemisphere	UBERON:0002245	60.51	gold quality
leukocyte	CL:0000738	60.34	gold quality
mucosa of stomach	UBERON:0001199	60.28	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.71	gold quality
muscle of leg	UBERON:0001383	59.68	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	59.33	gold quality
gastrocnemius	UBERON:0001388	59.27	gold quality
liver	UBERON:0002107	59.05	gold quality
lower esophagus mucosa	UBERON:0035834	59.02	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.18

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.