PES1-AS1

Summary

PES1-AS1 (PES1 antisense RNA 1, HGNC:58216) is a long non-coding RNA gene on chromosome 22q12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58216
Approved symbol	PES1-AS1
Name	PES1 antisense RNA 1
Location	22q12.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000223831
Ensembl biotype	lncRNA
Entrez	139355221
RNAcentral	URS0000024106 — lncRNA, 249 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000432130

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000432130 — 3 exons

Exon	Start	End
ENSE00001606310	30598309	30598363
ENSE00001610303	30606592	30606687
ENSE00001787131	30601818	30601915

Expression profiles

Bgee: expression breadth broad, 96 present calls, max score 89.99.

Top tissues by expression

96 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.99	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.42	gold quality
prefrontal cortex	UBERON:0000451	71.83	gold quality
left testis	UBERON:0004533	68.31	gold quality
testis	UBERON:0000473	68.14	gold quality
skeletal muscle tissue	UBERON:0001134	68.10	gold quality
right testis	UBERON:0004534	68.09	gold quality
muscle tissue	UBERON:0002385	67.12	gold quality
sural nerve	UBERON:0015488	65.98	silver quality
primary visual cortex	UBERON:0002436	65.46	gold quality
monocyte	CL:0000576	64.80	gold quality
islet of Langerhans	UBERON:0000006	64.35	gold quality
fundus of stomach	UBERON:0001160	63.55	gold quality
vermiform appendix	UBERON:0001154	63.34	gold quality
blood	UBERON:0000178	62.18	gold quality
liver	UBERON:0002107	61.92	gold quality
lymph node	UBERON:0000029	60.29	gold quality
cortex of kidney	UBERON:0001225	60.24	gold quality
endocervix	UBERON:0000458	59.24	gold quality
pancreas	UBERON:0001264	58.93	gold quality
right lobe of liver	UBERON:0001114	58.43	gold quality
muscle of leg	UBERON:0001383	58.42	gold quality
gastrocnemius	UBERON:0001388	58.02	gold quality
body of pancreas	UBERON:0001150	57.50	gold quality
stomach	UBERON:0000945	57.19	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	56.42	gold quality
body of stomach	UBERON:0001161	56.14	gold quality
heart left ventricle	UBERON:0002084	55.60	gold quality
tibial artery	UBERON:0007610	55.54	gold quality
metanephros cortex	UBERON:0010533	55.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.