PEX5L-AS2

Summary

PEX5L-AS2 (PEX5L antisense RNA 2, HGNC:41252) is a long non-coding RNA gene on chromosome 3q26.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41252
Approved symbol	PEX5L-AS2
Name	PEX5L antisense RNA 2
Location	3q26.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000244302
Ensembl biotype	lncRNA
Entrez	101928790
RNAcentral	URS000075C226 — lncRNA, 680 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000462801, ENST00000786147, ENST00000786148, ENST00000786149, ENST00000786150, ENST00000786151

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000462801 — 3 exons

Exon	Start	End
ENSE00001924624	179901926	179902086
ENSE00004162611	179898194	179898351
ENSE00004162612	179921550	179921899

Expression profiles

Bgee: expression breadth broad, 85 present calls, max score 91.86.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0414 / max 31.1249, expressed in 5 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
39950	0.0130	4
39947	0.0103	3
39948	0.0092	3
39949	0.0090	4

Top tissues by expression

196 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.86	gold quality
left testis	UBERON:0004533	85.69	gold quality
right testis	UBERON:0004534	83.57	gold quality
testis	UBERON:0000473	83.00	gold quality
sural nerve	UBERON:0015488	69.85	gold quality
corpus callosum	UBERON:0002336	67.39	gold quality
cortical plate	UBERON:0005343	65.23	gold quality
sperm	CL:0000019	65.02	silver quality
adult organism	UBERON:0007023	59.89	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	57.26	gold quality
monocyte	CL:0000576	56.24	gold quality
spinal cord	UBERON:0002240	55.70	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
ileal mucosa	UBERON:0000331	54.15	silver quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
epithelial cell of pancreas	CL:0000083	53.48	gold quality
prefrontal cortex	UBERON:0000451	53.22	gold quality
medial globus pallidus	UBERON:0002477	51.68	silver quality
Brodmann (1909) area 9	UBERON:0013540	51.46	gold quality
substantia nigra	UBERON:0002038	51.32	gold quality
islet of Langerhans	UBERON:0000006	50.64	gold quality
pancreatic ductal cell	CL:0002079	50.37	silver quality
tibialis anterior	UBERON:0001385	50.37	silver quality
body of pancreas	UBERON:0001150	50.32	gold quality
myocardium	UBERON:0002349	50.25	gold quality
pancreas	UBERON:0001264	50.00	gold quality
midbrain	UBERON:0001891	49.94	gold quality
anterior cingulate cortex	UBERON:0009835	49.86	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.