PFKFB3-AS1

Summary

PFKFB3-AS1 (PFKFB3 antisense RNA 1, HGNC:58068) is a long non-coding RNA gene on chromosome 10p15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58068
Approved symbol	PFKFB3-AS1
Name	PFKFB3 antisense RNA 1
Location	10p15.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000213994
Ensembl biotype	lncRNA
Entrez	124902371
RNAcentral	URS0002A25F26 — lncRNA, 524 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000427630, ENST00000729486, ENST00000729487

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000427630 — 2 exons

Exon	Start	End
ENSE00004057095	6197604	6197795
ENSE00004057097	6202440	6202771

Expression profiles

Bgee: expression breadth ubiquitous, 147 present calls, max score 81.63.

Top tissues by expression

251 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.63	silver quality
right uterine tube	UBERON:0001302	78.06	gold quality
sural nerve	UBERON:0015488	70.43	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.52	gold quality
muscle of leg	UBERON:0001383	65.04	gold quality
gastrocnemius	UBERON:0001388	64.87	gold quality
bone marrow cell	CL:0002092	64.02	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	63.62	gold quality
stromal cell of endometrium	CL:0002255	62.57	gold quality
descending thoracic aorta	UBERON:0002345	62.39	gold quality
metanephros cortex	UBERON:0010533	61.96	gold quality
monocyte	CL:0000576	59.60	gold quality
ascending aorta	UBERON:0001496	59.43	gold quality
thoracic aorta	UBERON:0001515	59.13	gold quality
omental fat pad	UBERON:0010414	58.66	gold quality
peritoneum	UBERON:0002358	58.61	gold quality
right coronary artery	UBERON:0001625	58.16	gold quality
prefrontal cortex	UBERON:0000451	57.76	gold quality
adipose tissue of abdominal region	UBERON:0007808	57.71	gold quality
mucosa of stomach	UBERON:0001199	57.49	gold quality
aorta	UBERON:0000947	56.79	gold quality
islet of Langerhans	UBERON:0000006	56.64	gold quality
lymph node	UBERON:0000029	56.05	gold quality
subcutaneous adipose tissue	UBERON:0002190	56.03	gold quality
blood	UBERON:0000178	55.99	gold quality
fallopian tube	UBERON:0003889	55.54	gold quality
gall bladder	UBERON:0002110	55.12	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	55.12	gold quality
pituitary gland	UBERON:0000007	54.95	gold quality
popliteal artery	UBERON:0002250	54.79	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.