PFN2-AS1

Summary

PFN2-AS1 (PFN2 antisense RNA 1, HGNC:55631) is a long non-coding RNA gene on chromosome 3q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55631
Approved symbol	PFN2-AS1
Name	PFN2 antisense RNA 1
Location	3q25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000242791
Ensembl biotype	lncRNA
Entrez	121832804
RNAcentral	URS0002A3EA3F — lncRNA, 803 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000323689, ENST00000471176, ENST00000726132

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000323689 — 2 exons

Exon	Start	End
ENSE00001831308	149978098	149978224
ENSE00001854171	149979152	149979355

Expression profiles

Bgee: expression breadth ubiquitous, 125 present calls, max score 87.67.

Top tissues by expression

125 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.67	gold quality
right uterine tube	UBERON:0001302	85.68	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.33	gold quality
gastrocnemius	UBERON:0001388	78.85	gold quality
muscle of leg	UBERON:0001383	77.52	gold quality
hindlimb stylopod muscle	UBERON:0004252	74.16	gold quality
cortical plate	UBERON:0005343	72.54	gold quality
cerebellar hemisphere	UBERON:0002245	71.92	gold quality
cerebellar cortex	UBERON:0002129	71.85	gold quality
skeletal muscle tissue	UBERON:0001134	71.84	gold quality
cerebellum	UBERON:0002037	71.65	gold quality
right hemisphere of cerebellum	UBERON:0014890	71.64	gold quality
right frontal lobe	UBERON:0002810	70.04	gold quality
primary visual cortex	UBERON:0002436	69.57	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	68.98	gold quality
Brodmann (1909) area 9	UBERON:0013540	68.80	gold quality
fallopian tube	UBERON:0003889	68.69	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	68.24	gold quality
frontal cortex	UBERON:0001870	67.49	gold quality
cerebral cortex	UBERON:0000956	67.34	gold quality
ganglionic eminence	UBERON:0004023	67.22	gold quality
Ammon’s horn	UBERON:0001954	66.46	gold quality
anterior cingulate cortex	UBERON:0009835	66.07	gold quality
prefrontal cortex	UBERON:0000451	65.46	gold quality
corpus callosum	UBERON:0002336	65.24	gold quality
nucleus accumbens	UBERON:0001882	64.78	gold quality
right coronary artery	UBERON:0001625	64.69	gold quality
brain	UBERON:0000955	64.57	gold quality
bone marrow cell	CL:0002092	64.17	silver quality
right lung	UBERON:0002167	64.09	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.27

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.